A Caution about Modeling Analog Addiction
by , 06-02-2011 at 09:19 PM (2037 Views)
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Some time ago, I created a model where I theorized two things:
1. Some folks have a high predisposition to nicotine addition and others a low predisposition.
2. Some folks have a high predisposition to tobacco MAOI addiction and others a low predisposition.
Another way to put this is to suggest that some folks who smoke do it because the nicotine calms them, and others smoke because the non-nicotine MAOI's calms them.
I then crossed these two theoretical scales as if on a sheet of graph paper to create four quadrants surrounding the origin (0,0).
The x-axis was defined as predisposition to nicotine addiction/nicotine's "feel good" ability. To the left of the origin (negative x-axis values), one is less and less affected by nicotine. To the right of the origin (positive x-axis values), one is more and more affected by nicotine.
Similarly, The y-axis was defined as predisposition to tobacco MAOI addiction/tobacco MAIO "feel good" ability. Down from the origin (negative y-axis values), one is less and less affected by tobacco MAOI's. Up from the origin (positive y-axis values), one is more and more affected by tobacco MAOIs.
Numbering the quadrants thus created from 1 to 4 (starting at the lower left and numbering in a counter-clockwise manner, we get the follow quadrants:
4 | 3
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1 | 2
In quadrant 1, low nicotine predisposition/medicative potential meets low MAOI predisposition/medicative potential. You don't really desire or need either one.
In quadrant 2, high nicotine predisposition/medicative potential meets low MAOI predisposition/medicative potential. You really like your nicotine, and it gives you relief. You really don't care all that much about tobacco MAOIs, they hold little appear for you and they hold little sway over you.
In quadrant 3, high nicotine predisposition/medicative potential meets high MAOI predisposition/medicative potential. You like everything about smoking except the smoking. You get strong relief from both nicotine and tobacco MAIO's.
In quadrant 4, low nicotine predisposition/medicative potential meets high MAOI predisposition/medicative potential. You really aren't smoking for the nicotine, you're smoking for all the tobacco MAOI's that are making you feel better of whatever ails you.
I'll say it again since it's taken on a life of it's own since I first posted it:
THIS IS ONLY A MODEL!!!
If it helps you to understand your addiction to analogs or if it helps you to understand why regular nicotine only e-cigs work well or poorly for you, great!! If it helps you to understand why snus does such a good job for you, great!! But there's not any reality to saying, "I'm in quadrant 1", or "I'm in quadrant 3", outside of understanding this as a subjective model.
Once could argue for or against the basic premises of the model, 1) that there's variable addition/efficacy profiles in individuals to nicotine and tobacco MAOI's, and 2) that crossing these arguable scales to create quadrants results in data that has any real meaning.
It's just a tool.







