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Originally Posted by Kurt

It is my understanding that TSNAs in non-fire-cured tobacco is from fermentation, not oxidation. Oxidation is reaction with O2. In order to make nitrosamines, nitrogen oxide must be introduced, not just O2. Fire-curing does this too. Increase in snus TSNAs is probably from open-air bacteria starting to eat the tobacco. With just reaction with O2, free-base nicotine should not turn into TNSAs, just nicotine-oxides, which are not considered harmful.

I found this on long-term increase

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The thing you need to remember about carto tanks is: As long as the tanks doesn't leak, it's all about the cartos and juice, not the tank. Inexpensive tanks will function just as well as the pricier ones. If you have issues with your tanks frosting or cracking, make the switch to polypropylene or glass tanks. I have also found that using cartos in a tank will significantly prolong their life. Also, since the carto is always being fed, the coil stays wet, and you won't have to worry about vaping ...