DIY e-liquid and nicotine extract method

[scrubadub]

Originally Posted by TribbleTrouble

Another good source of known quantities of Nic is the carts for the Nicotrol Inhailer. Each cart contains 10 mg of Nic (4mg delivered when using the Inhailer). If you pop out the white inserts in the carts and soak them in Everclear (Pure Grain Alcohol), you can extract the Nic without any worry of glue like with the patches. I have made a few batches, and it seems to work pretty good. Has anyone else tried this?

Yes I tried that last month and it worked for me as well. Definitely expensive if you're a 36mg fan but 18mg is as high as I go so it seems a viable option for me if things turn sour.

[jbbishop]

Here's some information that pins down the nicotine content of transdermal patches and which details the known or potential ingredients of the various product brands. I would imagine a great place to start would be in determining the solubility of the various compounds in the solvent you intend to use and then to assess the potential success of separation using filtration techniques taking into account the various binding properties. Barring that I imagine one would at least want to research the potential toxic effects of the inhalation of any of the ingredients which, in addition to nicotine, might be left over if there isn't any certain method of removing them.

What form(s) does Nicoderm come in?
21 mg/day
Each rectangular 22 cm² system contains nicotine 114 mg and provides 24-hour rate-controlled delivery of 21 mg/day to the patient. Nonmedicinal ingredients: ethylene vinyl acetate copolymer, polyisobutylene and high density polyethylene between polyester backings.

Walgreens Stop Smoking Aid Step 1 - 21 mg, Patches
Ingredients: Acrylate Adhesive , Aluminized Polyester , Cellulose Paper, Methacrylic Acid Copolymer

Equate: Stop Smoking Aid Patch Nicotine Transdermal System, 21 mg
Ingredients
Active Ingredients: Nicotine. Inactive Ingredients: Acrylate Adhesive, Aluminized Polyester, Cellulose Paper, Methacrylic Acid Copolymer.

Novartis Nicotine Transdermal System Patch 21 mg Step 1- 7 Patches
INGREDIENTS
Active Ingredients:Per Patch: Nicotine 21 mg Delivered Over 24 Hours.
Inactive Ingredients:Acrylate Adhesive; Aluminized Polyester; Cellulose Paper; Methacrylic Acid Copolymer.

Nicotine is well suited for transepidermal delivery because it is a liquid which is known to penetrate skin easily. In fact, there are documented cases of tobacco workers suffering from nicotine overdose as a result of handling raw tobacco leaves, a condition known as Green Tobacco Sickness. Depending on the type of patch, the amount of nicotine compound employed varies between 5% and 50%. The drug may be used in its pure form, or it may be linked with other chemicals entities such as hydrochloride, dihydrochloride, sulfate, tartrate, bitartarate, zinc chloride, and salicylate to form derivatives.

When preparing patches with these chemicals, there are two key areas of concern. The first is dosage, since too high a dose can cause irregular heartbeat, palpitations, nausea, vomiting, dizziness, or weakness. In fact, 60 mg of nicotine (the equivalent of smoking 60 cigarettes at once) is considered to be a lethal dose. Therefore, it is critical that the patch be calibrated to deliver the prescribed amount. The second consideration is related to the solvent properties of nicotine. The drug will attack or dissolve many of the materials used to make patch components. Many adhesives, for example, become stringy and loose their tackiness when exposed to nicotine. Or, they may become so heavily loaded with the drug that they deliver an unacceptably large burst of nicotine when attached to the skin. The compatibility of all patch materials that contact nicotine must be carefully evaluated.

Delivery vehicle

The patch itself is a small disk approximately 1 in (2.5 cm) or less in diameter, which may be assembled in several different configurations. One type of patch consists of a plastic chamber that contains the drug and is covered by a selectively permeable membrane to control the rate at which the drug is delivered. This carrier layer can be made from a variety of plastics, including polyvinyl chloride, polystyrene, polyurethane, ethylene vinyl acetate, polyester, polyolefin, and polycarbonate. Alternately, the carrier may be of the matrix type, also known as the monolith type. In this configuration, the drug is dispersed or suspended in the solid plastic matrix of the carrier. In yet another patch design, the drug is mixed directly with the adhesive and applied to a plastic support layer. Regardless of which patch design is employed, the disk must deliver the drug at a controlled rate. It is also important that the device be made from a plastic material which is flexible enough to be applied and removed from skin without breaking or tearing.

Backing layer

All patch configurations feature an occlusive backing layer that is impermeable to the drug. This is typically a plastic sheet laminated with metallic foil to increase its barrier properties and prevent the drug from leaking.

Adhesive

The adhesive used to mount the patch on the skin is extremely important. There are a number of medical grade, pressure-sensitive adhesives, such as acrylate ester/vinyl pyrrolidone copolymers, dimethyl silicone polymers, and acrylate polymers. The latter dominate medical adhesive market, mainly because of their low level of allergenicity. In addition to being nonirritating to the skin, a patch adhesive must have good water resistance so it continues to adhere when the skin perspires. It must have sufficiently high cohesive strength to allow clean removal of adhesive from skin, and it must have properties that allow it to accommodate skin movement without losing the bond and without excessive skin irritation. As described above, care must be taken to ensure the adhesive will not degrade after prolonged contact with nicotine.

Other ingredients

Other ingredients, such as pigments, dyes, inert fillers, and processing aids, may be mixed in with the drug. Certain types of patches also include permeation enhancers to improve drug penetration. For example, one manufacturer of transepidermal patches includes low levels of alcohol to enhance skin penetration. Some nicotine patches contain antipruritic (anti-itch) agents to treat the pruritus associated with transdermal delivery of nicotine. These antipruritic drugs are selected from a group consisting of bisabolol, oil of chamomile, chamazulene, allantoin, D-panthenol, glycyrrhetenic acid, corticosteroids, and antihistamines.

[TribbleTrouble]

Yeah, that glue has a lot of crap in it. Wouldn't want to breath that in!

[hason74]

Originally Posted by rlorange

Hello just a quick note but I think you will like!

Nicotine patches have 140mg of nicotine in them which is easily extracted with a little alcohol or pure acetone (which will all evaporate later)

Simply soak a patch in acteone and let evaporate in eye dropper bottle you will be left with pure nicotine crystals (and maybe some glue, have to work out how to get rid of that!)

then add glycerine and flavour to the bottle to disolve. No carcinogenic tobacco extract stuff, measured dose, one patch makes a few mls.

hmmmmmm

The glue wont be a problem if u use acetone, u just have to "rinse it" after u get the ni' crystals, put them in a bowl, pour in acetone, put on rubber gloves and knead the crystals in the acetone, the glue will go into the acetone, u then pour the acetone out, not letting the crystals leave the bowl.

did that make sense?

[jbbishop]

Well this looks stupid:

Smoking - tobacco + nicotine extract [Archive] - Drugs Forum

[StratOvation]

Originally Posted by hason74

The glue wont be a problem if u use acetone, u just have to "rinse it" after u get the ni' crystals, put them in a bowl, pour in acetone, put on rubber gloves and knead the crystals in the acetone, the glue will go into the acetone, u then pour the acetone out, not letting the crystals leave the bowl.

did that make sense?

No, Actually It makes no more sense to assume light, manual agitation in a bowl of acetone would solubilize and retain all unwanted agents from the crystal than it makes to assume, a simple acetone rinse of a ni patch would yield a pure ni crystal to begin with.

[b00stzx3]

So how do the "pros" do it, like where Puresmoker and Totally Wicked get theirs from?

has anyone thought abotu nico-gum? its usually cheaper than the patches (can get it on ebay) and has plenty of nicotine.

[Lithium1330]

Originally Posted by b00stzx3

So how do the "pros" do it, like where Puresmoker and Totally Wicked get theirs from?

has anyone thought abotu nico-gum? its usually cheaper than the patches (can get it on ebay) and has plenty of nicotine.

They buy from China, no suppliers that I know extract their own nicotine or produce e-liquid, they can ask the manufacturer for some changes on the formulation or flavor, that is it.

JC is another story, I don't know where they get their nicotine from.

[Denni]

Originally Posted by StratOvation

No, Actually It makes no more sense to assume light, manual agitation in a bowl of acetone would solubilize and retain all unwanted agents from the crystal than it makes to assume, a simple acetone rinse of a ni patch would yield a pure ni crystal to begin with.

My thought exactly.

But I think a few wipes with nail varnish remover might do the trick for removing some of the glue. Leave it to evaporate, then float the patch on a minimum volume of 90%VG/low calcium water and finally squeeze it (wear those gloves!)

Any thoughts?

[b00stzx3]

Nicotine Solution, 0.01 %, Laboratory Grade, 100 mL - Chemicals - Chemistry - Chemistry & Physics - Carolina Biological Supply Company

Anyone checked this out? Says its 100ml of labtratory-grade nicotine "solution". $20.00