Any interest in determining nicotine--by DVAP

[kinabaloo]

Possibly, I did feel (subjective) that I get a better/quicker 'hit' with very high
strength PEG juice than same strength but PG or VG,
might have been my expectations/imagination though.

But has a less 'smoky' vapour than PG.



Don't know how PEG metabolism goes at all,
probably far less info available for that than for PG.

I want a big bossom'd tutor as well, got any spare?

That smokeyness might be the more sugaryness of PG and VG and their slight drying effect; especially the latter.

[kinabaloo]

How viscous is PEG-400 exo?

More so than VG (i guess so if it solidifies in the fridge).

[DVap]

Viscosities in cSt, at approximately room temperature:

PG: 52
PEG-400: 90
Glycerin: 648

Be careful not to assume correlations between viscosity and freezing points.

[kinabaloo]

Viscosities in cSt, at approximately room temperature:

PG: 52
PEG-400: 90
Glycerin: 648

Be careful not to assume correlations between viscosity and freezing points.

i didn't, that's why asked. was going to add 'but it doesnt necessarily follow', but i suspected it would

Room temp in uk is more like 15C, so almost halfway to fridge temps !

[DVap]

Room temp in uk is more like 15C, so almost halfway to fridge temps !

What the hell, man? Are you making lager in your den?

[kinabaloo]

What the hell, man? Are you making lager in your den?

Seriously, nobody here would choose 25C !

[DVap]

Y'all remember when we didn't care what we inhaled?

[DVap]

A lot of the discussion from which this concern arises is nicotine in tobacco leaf, not a fairly pure solution; so you could well be right.

The complex matrix that is tobacco leaf has lead to agents like ammonia being graciously added to tobacco leaf in cigarettes precisely to help drive the nicotine towards the base. It's likely the electron pair (proton acceptor) in ammonia that's not in the vicinity of a conjugated (electron delocalized) system that accounts for it's much higher base strength than that of nicotine or other conjugated pyridine derived bases.

As an aside, if you've never smelled pyridine, you've missed a real treat. I last used it back in a research lab in college for... hell, I can't remember, maybe something to do with polyimides... but it'll get your attention. "Penetrating fish-stench" doesn't even begin to describe it.

[Vaporer]

I found an interesting article on pH an adsorbtion. At 5.5-6pH from burning tobacco the lungs effectivly adsorb it. At pH's of 6.5-7.5 it's readily adsorbed in the mucous membranes of the mouth. So, they add sodium bicarbonate to snus. No surprize there.

Wouldn't we adsorb more nicotine if our juice vapor was in the higher pH range? It's been stated that less vapor makes it to lung tissue compared to smoking and PG & VG's affinity to want to hold the nic.

A handbook on drug and alcohol abuse ... - Google Books

This thread is a great read and info to all of you posting.

Thanks!

[DVap]

I found an interesting article on pH an adsorbtion. At 5.5-6pH from burning tobacco the lungs effectivly adsorb it. At pH's of 6.5-7.5 it's readily adsorbed in the mucous membranes of the mouth. So, they add sodium bicarbonate to snus. No surprize there.

Wouldn't we adsorb more nicotine if our juice vapor was in the higher pH range? It's been stated that less vapor makes it to lung tissue compared to smoking and PG & VG's affinity to want to hold the nic.

A handbook on drug and alcohol abuse ... - Google Books

This thread is a great read and info to all of you posting.

Thanks!

The pH of e-liquid seems plenty high enough to absorb whether it be mucous or pulmonary.

We may very well be looking at particle size? Cigarette smoke has a very small particle size, while I would suspect that vapor particle size is much larger. If we view vapor as a solvent/solute system, where nicotine is the solute (the stuff dissolved) and PG is the solvent (the stuff doing the dissolving), then a "particle" of PG would present to the lungs as a container, the contents of which (nicotine) aren't readily obtainable. The bigger the container (particle), the more content (nicotine) is hidden from the view of the lungs.

Plausible?