Just some thoughts from my own experience regarding the 'throat hit'....
It's the nicotine content of the juice....without a doubt the higher the better. It's the quality of the juice. It's how much juice is in your cart. It's a freshly charged battery and the quality of that battery. It's the way you inhale. It's the length of the cutoff of the e-cig you are using (with a manual battery where you control the cutoff being the best) and it's the quality of the atomizer in the type of e-cig you are using.
The atomizer really seems to be the major key in the equation and that's where you run into quality control problems. For example, the 401 is an e-cig which many people like and praise. But the 401 I purchased was so bad I returned it, and I had 2 atomizers with it. But does that mean all 401s are bad? No, it just means the one I had with it's two atomizers was.
My 901 was just Ok with it's first atomizer, but kicks my throat in a nice way with the 2nd one.
My 501 with a manual battery where I can contol the cutoff time is the best of all. The manual battery is a big part of that, but mostly it's because the atomizer in a 501 is the best I've experienced. It just seems to be more powerful and heats the liquid more. I really believe the heat of what you are inhaling is the main key to the throat hit. So when it comes to atomizers the ones that are able to heat the liquid the most are the best. They may get so hot that you feel it while holding it, but that's something I'll never complain about because the throat hit is so good! With that said, I'm sure there are people who have purchased 501s with a bad atomizer and they gave up on the 501. Here again, it's the quality control part of it.
Anyway, that's just my opinion after a night on the town and vaping a lot of 24mg liquid....

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