Inhaling PG - perhaps not the great unknown after all

[Kate]

Great find Billster, here's the link - http://www.supersmokerjp.com/images/...anslatiion.pdf

I'm not sure what is being said about propylene glycol but the tests on glycerine are very promising, I'll mention this on the thread about glycerine.

[Kate]

This information might be of interest to some of you, it's about the hazards of propylene glycol in theatrical fogs. It says that pg might cause respiratory tract problems and eye irritation. It doesn't appear too worrying to me though, unless you're sensitive to pg I think the concentration required to cause problems would be higher than we could achieve by vaping it.

http://www.dow.com/PublishedLiteratu...romPage=GetDoc

[ApOsTle51]

i just found this quite extensive study into PG. bit of light reading for ya

Propylene Glycol excerpted from NTP-CERHR expert panel on the reproductive and developmental toxicity of propylene glycol - The Center For The Evaluation Of Risks To Human Reproduction (CERHR) NTP-CERHR-PG-03 May 2003

enjoy

[TropicalBob]

Killed this cause I was responding to an earlier post here (where a link took me).

[jigtg]

@prestontiger: MSDS is for handling not using.

Propylene glycol (PIM 443) contains much better info. It talks about ADI of 25 mg/kg and with e-cigs you would get 20(number of cigs)*0.1ml=2ml per day. Assuming 100% PG here. For a 75 kg person(me ADI would be 1875mg which is about 1.8ml given PG density of 1.036 g/cm³.
It is worth pointing out that you might already be receiving 1.8ml from food and other stuff per day. There is just no easy way to know. ADI recommendations do include safety factors, so I wouldn't personally be too worried about these limits exceeding.

adi "propylene glycol" - Google Search list plenty of good docs. http://www.health.gov.mt/fsc/fschome...ate_sum_en.pdf for instance talks about ADI of 0.5 mg/kg.

In practice, something like 50% of PG is exhaled so 2ml*0.5 = 1ml per day.
50% being a wild guess. 85% PG 2ml*0.5*0.85 = 0.85000ml per day and 50% PG 2ml*0.5*0.50 = 0.50000ml per day.

[Kate]

I was just having a look at what Wikipedia had to say about propylene glycol - Propylene glycol - Wikipedia, the free encyclopedia They say that "Propylene glycol is metabolized into pyruvic acid, which is a normal metabolite in the breakdown of glucose ..."

"... pyruvic acid is converted into lactic acid, but if oxygen is available it is converted to acetyl coenzyme A, which enters the Krebs cycle." - pyruvic acid: Definition from Answers.com

Lactic acid - Wikipedia, the free encyclopedia

Acetyl-CoA - Wikipedia, the free encyclopedia

There's not much about lactic acid or acetyl CoA that caught my interest but I found this - EmphyCorp, Inc. - Pyruvate in Cancer Prevention & Treatment - pyruvic acid might help prevent and cure cancer. "Pyruvate will repair injured mitochondria to kill the tumor. Also we have discovered that pyruvate can “up-regulate” NO, which can kill viruses, infections, and tumors." [NO = Nitric Oxide]

"Alpha Keto Acids Including Pyruvate Increase Nitiric Oxide (NO) Levels Needed to Kill Viral Infections ..." - EmphyCorp, Inc. - Anti-Viral Effects of Nitric Oxide (NO)

It would be very cool indeed if it turns out that esmoking with propylene glycol can prevent or cure cancer.

[Kimmiegrif]

Kate, very cool. Thanks for sharing.

[gashin]

I was just having a look at what Wikipedia had to say about propylene glycol - Propylene glycol - Wikipedia, the free encyclopedia They say that "Propylene glycol is metabolized into pyruvic acid, which is a normal metabolite in the breakdown of glucose ..."

"... pyruvic acid is converted into lactic acid, but if oxygen is available it is converted to acetyl coenzyme A, which enters the Krebs cycle." - pyruvic acid: Definition from Answers.com

Lactic acid - Wikipedia, the free encyclopedia

Acetyl-CoA - Wikipedia, the free encyclopedia

There's not much about lactic acid or acetyl CoA that caught my interest but I found this - EmphyCorp, Inc. - Pyruvate in Cancer Prevention & Treatment - pyruvic acid might help prevent and cure cancer. "Pyruvate will repair injured mitochondria to kill the tumor. Also we have discovered that pyruvate can “up-regulate” NO, which can kill viruses, infections, and tumors." [NO = Nitric Oxide]

"Alpha Keto Acids Including Pyruvate Increase Nitiric Oxide (NO) Levels Needed to Kill Viral Infections ..." - EmphyCorp, Inc. - Anti-Viral Effects of Nitric Oxide (NO)

It would be very cool indeed if it turns out that esmoking with propylene glycol can prevent or cure cancer.

I noticed the lactate acid buildup my first week (i.e. muscles felt tired) but seems to have gone away.

[ApOsTle51]

It would be very cool indeed if it turns out that esmoking with propylene glycol can prevent or cure cancer.

lol ...how ironic would that be ...

[TropicalBob]

Couple this thread with the one on "germ-killing vapor" and we might just conclude that what we're doing is not only NOT HARMFUL, but is BENEFICIAL. We are medicating with every inhalation of vapor. And to think that some in power want to ban this practice ...