Current skinny on VG vs. PG. Dr Loi?

[paladinx]

who the hell knows. Doesnt make much sense to me though. Why wouldnt the lungs absorb it? I mean people inhale medications through inhalers through the lungs no?

[Tallgirl1974]

Originally Posted by Karen

I read somewhere that the vapor is not absorbed in the lungs, as in a cigarette, but only absorbed in the mouth and nasal passages. Can this be right ??

You saw it on the new info report someone posted? Thats where I read it.The nicotine is not in our lungs- the water vapor and PG/VG is. Just as with the nico inhaler, I believe, the nicotine is heavier and hitting and absorbing in our mouth/throats/top airways and not in our lungs. I tried to go find a direct quote but yanno its a mass mess of posts!

[Tallgirl1974]

Originally Posted by paladinx

who the hell knows. Doesnt make much sense to me though. Why wouldnt the lungs absorb it? I mean people inhale medications through inhalers through the lungs no?

This is my take on it: we don't directly pull the vapor into our lungs, we drag and hold in the mouth before we inhale.
With the others(inhalers and nebulizers) we directly inhale, deeply and quickly. Nebulizers do get the meds into the mouth/throat and airway. Thats why they ask patients to rinse the mouth out when done.
I have a theory that if you hit a PV like a doob more nic would be absorb into the lungs.

[ramblingrose]

Originally Posted by Tallgirl1974

I have a theory that if you hit a PV like a doob more nic would be absorb into the lungs.

Maybe; I don't know. I don't feel any kind of lung hit that way.

[taz3cat]

Big tobacco puts baking soda in smokeless tobacco because, nicotine's PH is to acid to be absorbed in the mouth. Baking soda raises the PH and the nicotine is absorbed. Swedish snus, uses it also, but they use different words more of a description of what it does.

Our e-juice is probably to acid for the lungs to absorb and we don't get as much nicotine as we think we do by mouth.

[katink]

Spirou - constipation is one of the long list of possible side-effects from stopping (or lessening a lot) the smoking of (real) cigarettes... It's very easy to mix up effects from something new you are starting on, with effects from stopping doing what you did before this new thing, whatever it is/was. But I guess it would be a good thing to always try to find out what the effects can be of both instances, not just the 'new' instance on which a person, very understandably, tends to concentrate when going from an 'old known' to a 'new unknown'.

[Kate51]

This whole theory about lungs/not lungs absorbing nicotine. Irrelevant.
The process seems to be happening, and where ever the vapor eventually deposits it's load of nicotine, it must somehow be making it's way to the brain's receptors. Or we wouldn't be bothering ourselves with whatever method of nicotine delivery we are using. And the strength of the liquid we know we can tolerate or not tolerate.
If it is absorbed by mucous membrane, mouth, nose, throat, or lungs it's absorbed. Trying to make sense of the studies done with patches, gum, inhalers, etc., the one bit of information that comes through is that absorbtion is faster with cigarettes, slower with any other means. Why that is is hard to discern from any study, but then again I am not a molecular scientist either. All we know is that we receive satisfaction for our efforts through inhaling vapor from PV's. Studies would have to be done IMHO of the mechanisms of the brain itself, which would take years of study just to verify the testing procedures, what the method of comparisons would be, and millions of dollars to do all of these studies to do a study, then technological development of scanning and sampling devices! Then someone would surely be handy to try to question or nullify the results. And the whole cycle would start all over again, by that time I don't think I'm going to be giving a rat's @$$ about it all. Today the question is, WHAT are we addicted to? If indeed we are addicted to anything. Maybe we just happen to like nicotine, as I like a Milky Way bar once in awhile. This is the same question that parents of Down's Syndrome children or MS victims or Autistim, and a host of maladys want to find the answer for. What happens, how does it happen and how do we fix it. I don't think right now today we can find difinitive answers. Or another way to think about it is why do I have ADD, and why doesn't my brain allow me to have 100% instant recall, or 100% Photographic memory. Science seems to be only trying to define the question, so far. Stay Tuned!

[paladinx]

I guess the more important question is how much nicotine are we getting. and the reports seem to conflict some peoples experiences while others agree whole heartily. Now why is that the case. Are some actually getting more, what are their habits compared to the other group. Is it a placebo?

[JoeSmog]

Originally Posted by No burn baby

Dr. Loi, I'm hoping you will read this.

Very simplistically, what is the current skinny on VG vs. PG. Are we right in thinking that VG is likely safer in general, even in the instance where no PG allergy exists? I don't want to find myself barking up the wrong tree by going out of my way to vape VG if the concerns are equal. I would be extremely grateful for advice on this matter.

Who is Dr. Loi? Why consult him? NASA has done this for you.

Look here at the most current data available. This chart should be a good indication of the known hazards of PG. See left of table for adverse end points. Compare to any symptom you feel you might have. Left for Time Intervals. Concentrations in Exposure column. Also realize that Rats/Mice have lungs that can drain. Human lungs cannot.

Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants: Volume 5

[paladinx]

Some of it is Chinese to me, but one part that bothered me was about thickening of the respiratory cells etc, and it said something about 2 mg, which is what about 2ml? Average amount people smoke?