NCi ECIG Clinical Trials looking for particapants

[Krakkan]

This is the news we all been hoping for me thinks! This study at least will show how effective these devices are for most people, and we dont have to be quaking in our boots as to weather our e-cigs are affective. It wont be the last study though, and we are certaintly not out of the woods yet.

Yeah I do feel this will be good

[Tom09]

Leading investigator: T. Eissenberg (Virginia Commonwealth University). So, that’s the study we could read about in previous news articles (April 7 Washington Post, June 2 NY Times).

Will be interesting in as much Eissenberg’s findings may confirm Laugesen/Ruyan-team’s first restults. Recalling this comment from Eissenberg to Kate: "These data, if they are valid and can be replicated, provide little support to the manufacturers' claim that the devices can do what they are marketed to do: deliver a physiologically active nicotine dose to the lung."

[Hangtime]

I think this study is great but I already did my own study. I bought e-cig and for some strange reason I havent had a tobacco cig since, hmmm, I didnt buy the e-cig to quit, that just happened by itself. Strangest thing happened too. My wife got her e-cig and didn't want any more 'analogs' either. My conclusion is e-cigs do help you smoke less or quit all together.


This test is very interesting and I cant wait to see the results.

[TheKingOfKool]

Why does it say in the description that they are being developed and marketed by the tobacco industry?

Are C7 or NJoy owned by a tobacco company?

if they are claiming its a tobacco product that doesn't fall under FDA jurisdiction then that means they ARE a tobacco company

[(So) Jersey Girl]

I'm new here and just found this old thread. Does anyone know if the results of this study have been published yet? Wouldn't it have made more sense if the researchers had used a FDA approved product like the Nicotrol Inhaler instead of an unlit cigarette if they're measuring nicotine delivery to the lungs? I mean, the main reason I see for so much opposition to ecigs is that they don't have FDA approval, so why not compare them to something that does?

[kristin]

I haven't seen any updates on this and I'm sure it would be all over the boards if they did publish something.

What they test against is relative to what they are trying to determine. If they are trying to determine if they are as safe as FDA-approved NRTs, then then they would use an NRT as a control. If they are trying to determine if they are "safer" than smoking tobacco cigarettes, then they would, logically, use a cigarette as the control. not sure about using an UNlit cigarette? Where did you see that? It makes no sense, as an unlit cigarette poses no danger to anyone!

EDITED TO ADD: Oh, I see. I looked at the link. They are testing it against an unlit cigarette (as sort of a plaecebo) but they are also testing it against a lit cigarette of the test subject's own brand.

[Vocalek]

The researcher is quoted in this story.

E-cigarettes gaining steam in Virginia, but are they safe? - NBC12 - NBC12 News, Weather Sports, Traffic, and Programming Guide for Richmond, VA |


We are getting very mixed messages here. This is part of the description of the study:

Evaluating the effects of these products is crucial to public health, as past industry-sponsored efforts at harm reduction (e.g., so-called "light" and "ultra-light" cigarettes) were not evaluated and failed to reduce carbon monoxide (CO), nicotine, and carcinogen exposure in smokers; these efforts thus failed to reduce the harms of smoking (Stratton et al., 2001).

So it looks as if one goal for harm-reduction products is to reduce the amount of nicotine (although how that reduces the smoking-related diseases isnt clear to me). But in the TV story, it looks as if the researcher's complaint is that the e-cigarette might not deliver enough nicotine.

"If there's not any consistency in what's in the cartridge, then how do we know that there's gonna be any consistency in the effects they produce?" said Dr. Thomas Eissenberg with the VCU Institute for Drug & Alcohol Studies.

I assume that this next paragraph actually refers to Dr. Eissenberg. I have to wonder, after reading the description of his study, why he is bringing up safety, when that was not the topic of the study.

"If this is a safe way of delivering nicotine that keeps people away from cigarettes, then I'm all for it. The question is: Is it safe?" Dr. Thomas said.

There are no results posted on the Clinical Trials page for this study.

[(So) Jersey Girl]

Thanks for your replies.

I was curious about this because it seems that the main objection to e-cigs is the lack of FDA approval of them as a drug delivery device, which to me means "smoking cessation." So compare them to what's on the market. I personally did not switch to PV's to quit smoking. And, like Dr. Seigal said on his blog, the question they should be asking is not "Are they safe?" but whether they are safer than tobacco cigarettes.

[(So) Jersey Girl]

I guess I should have been a little more patient and waited a couple of days.

[Vocalek]

The results are out. Here is a discussion http://www.e-cigarette-forum.com/for...com-today.html