Cigarette or Drug

[LaceyUnderall]

In order to get them approved they had to lower the dosages so that the NRT itself wouldn't be addictive. The FDA Approved inhaler delivers about 12% of the Nicotine of a full flavor cig.... Doubling NRTs would give a higher dose (Closer to what they were getting by smoking) and the gum or lozenge would spike the dose closer to those levels during strong cravings.

We are also forgetting about the other alkaloids in tobacco, like the harmala alkaloids, which are MOA inhibitors..

And then we have delivery methods-- e-cig nic is absorbed in the upper portions of the respiratory tract, gums and lozenges through the skin in the mouth, Nicotrol (The inhaler) through the lining of the mouth, the patch- through the skin, and tobacco which is through the lungs , mouth lining, and upper respiratory system. It effects how fast the nic is available to the body... The patch designed to give you a steady low dose all day long- where as smoking hits you (Highest levels of nic in your blood) at around 14 min, e-cigs about 19.5 min, and the Nicotrol at 30 mins.

These low nic cigs are probably likely to be addictive as they most likely contain the other alkaloids in tobacco still.

Congress, the ANTI-Smoking groups, and the FDA ares so obsessed about Nic that they have missed over a decade of research that was looking at MOAIs + Nic as the possible cause of the severe addiction.

What I think is most interesting about the OP lower nicotine cigarette is the fact that it still uses combustion. It's the combustion that is the bad part of the smoking experience.

As many of us have learned, those first three weeks without combustion, we are missing something. Carbon monoxide, arsenic, and many other combustion by-products are just as addictive as the nicotine.

The ecig has definitely provided the scientific community the ability to really go back and evaluate the true manner of addiction when it comes to smoking. Is it really the nicotine addiction or is it so much more? I argue more. I argue that the nicotine addiction is really nothing in comparison to the other addictive qualities and actions involved in smoking.

[lotus14]

What I think is most interesting about the OP lower nicotine cigarette is the fact that it still uses combustion. It's the combustion that is the bad part of the smoking experience.

As many of us have learned, those first three weeks without combustion, we are missing something. Carbon monoxide, arsenic, and many other combustion by-products are just as addictive as the nicotine.

The ecig has definitely provided the scientific community the ability to really go back and evaluate the true manner of addiction when it comes to smoking. Is it really the nicotine addiction or is it so much more? I argue more. I argue that the nicotine addiction is really nothing in comparison to the other addictive qualities and actions involved in smoking.

Nicotine addiction is not equal to smoking addiction. By a long shot. You can wear 4 patches while chewing nicorette until you're shaking and sweating from the nic od and want a cigarette to calm you down.

My guess is the nicotine, MAOIs, the ritual, and the mental circuitry built up over the years which associates the the throat and lung hit with the pleasurable effects of smoking combine to making quitting so tough.

No wait, quitting smoking is easy - I've done it a hundred times!