kinabaloo
PV Master
ECF Veteran

Originally Posted by kinabaloo

I would be interested to know if the simple combination of nicotine and anatabine*, in appropriate ratio, would be as effective as WTA (possibly even beter). The obvious omission being the more minor harmala alkaloids that have some reasons to be thought possibly important. On the other hand, one could avoid nornicotine.

To my mind this combination would still be a tobacco extract, little more complex that just nic. 50/50 if it would be as effective (or more accurately, as effective

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Originally Posted by kinabaloo

Indeed, harm reduction is about efficacy (effective, safer alternative one doesn't need to over-use) and that includes satation - which needs include a 'hit'; as you said, even the WTA if weakened sufficientlt by a bad device will not create that impact + satiation.

Ride a roller and the buxx lasts. Imagine riding it at 1/4 speed. Would going around for 4x as long be as good? Or even 10x ?

Originally Posted by kinabaloo

People may wonder just what is the difference between WTA and nic-only e-liquid.

And note that this only applies to those who 'need' it.

A few analogies come to mind ...

If one buys a atandard bar of chocolate one can ('must' even) much the whole lot in one go; whereas a high quality chocolate satisfies in small measure and more greatly appreciated. One can delve into the bio-psychology of endorphins and more if one wishes, but it is clear that the cheaper,

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Originally Posted by kinabaloo

Although one could sort-of have a nicotine-free WTA, it would no longer be WTA !

Only a small fraction of the alkaloids in tobacco make it into the body when smoking; a lot is just combusted as it can't vaporise/escape from the matrix. The profile of alkaloids in smoke will be somewhat different from that of the tobacco itself (and also between different types of tobacco) as each alkaloid will have a somewhat different boiling point and strength of salt bond, particle size to escpe

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Originally Posted by kinabaloo

Indeed, it is not the nicotine that causes the symptoms, but as I have been saying, 'the use of nicotine-alone'. I think I see the confusion now; to be absolutely clear - it is the absence of the other alkaloids that can lead, in some people, to these symptoms, not the nicotine itself.

However, further, it is logical that continued use of just-nic could, for these people, make these symptoms worse, because it will be pushing the imbalance (stoking the craving for the missing alkaloids).

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