Introducing Nhaler High Voltage Octane Liquids-10Mg 100% USA MADE in Forum Suppliers; Awesome, can't wait to try these! You're the man Drew, and thanks a bunch for sending those tweezers that I ...
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Senior Member
ECF Veteran
Awesome, can't wait to try these! You're the man Drew, and thanks a bunch for sending those tweezers that I hoped for with my last order!!! Now I have all the tools I need
Love you guys...
Quit on November 25, 2009 around 3:30 PM.
Black Silver Bullet & Xhaler with all the fixin's.
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Edited for clarity
Drew,
While I have no intention of disparaging the liquid (Nhaler is good stuff), I can't let pass the statement that many or all current liquids on the market contain D-nicotine. This is simply incorrect. Not being the natural stereoisomer of nicotine, D-nicotine is actually prohibitively expensive.
If one were to check the pricing at Sigma Aldrich, 1 gram of racemic nicotine (containing equal amounts of L and D nicotine) can be had for $413.50. 500 mL (505 grams) of L-nicotine can be had for $804 or $1.59 per gram. You can't even get pure D-nicotine from Sigma Aldrich (and if you could, it would probably go for over $1000 per gram. The simple reason for 1 gram of racemic nicotine being 260X more expensive than 1 gram of L-nicotine is that L-nicotine is natural and racemic nicotine is not, it had to be synthesized from non-nicotine starting materials.
L-nicotine is the enantiomer of nicotine isolated from tobacco, and is the enantiomer used in all e-liquds.
Since I have no doubt that you're on the up and up, I've got to assume that someone you're dealing with has been feeding you a line.
Last edited by Drewsworld; 02-26-2010 at 04:28 PM.
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Super Member
ECF Veteran
Edited for clarity
It's true that d-nicotine is quantitatively much less active than l-nicotine (animal studies here, here, and here), but l-nicotine is what we should have been getting all along, correct?
Drew, I'm not sure where you are getting the information that e-liquids commonly contain d-nicotine, though I would be very interested to see data if any of them do.
L-nicotine, which (as you quote) is the naturally-occurring form in tobacco, is what should be present in all of our eliquids, given that they are all extracted from tobacco.
Snus contains l-nicotine because it is a tobacco product; cigarette smoke delivers l-nicotine; eliquid should contain l-nicotine because it is a purified product of tobacco....and while I'm unfamiliar with the extraction process, I'm not sure how it could alter the isomer itself.
(ETA: Sorry for the redundant post...DVap beat me to it.)
(And to add: I love my Xhaler and it's always been a pleasure doing business with you, Drew... I'm just quite curious about this.)
Last edited by Drewsworld; 02-26-2010 at 04:29 PM.
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[QUOTE=Hellen A. Handbasket;1089608]Sounds like just what I'm looking for (I get tired of using snus).
I guess I am a little confused by your comment Helen. Since this new liquid has the same type of nicotine as snus, does that mean it has the alkaloids that snus does?
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Originally Posted by
hittman
I guess I am a little confused by your comment Helen. Since this new liquid has the same type of nicotine as snus, does that mean it has the alkaloids that snus does?
Nope. Snus owes it whole tobacco alkaloid profile to the fact that it is processed tobacco. Purified nicotine loses the rest of the tobacco alkaloid profile. The strong point of this liquid, as I see it, is that it is entirely U.S. made (a good thing), and is made from pharmaceutical grade nicotine. High quality starting materials = high quality product.
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Forum Supplier
ECF Veteran
When I was initially introduced to these liquids I immediatley noticed that they appeared much stronger...When I asked the lead Chemist why he went into a long winded explanation that I had a hard time understanding...But he did make clear the word Levarotatory and told me that was the reason...I then did some research on my own and found many studies clearly showing that the the effects of L-Nic was stronger...I therefore assumed that if L-Nic was used in this and it was stronger then the other must be D-Nic...
Below is one of the studies I found with a link and a quote
SpringerLink - Journal Article
Dose-response relationships for optically pure (-)- and (+)nicotine as well as antagonistic effects were examined in both groups of rats. The natural isomer (-)nicotine was approximately nine-times more potent than (+)nicotine. Mecamylamine produced equal blockade of the (-)- and (+)nicotine cues. Hexamethonium and atropine were without effect. These data demonstrate the possible stereospecificity of the central nicotinic receptor that mediates the stimulus effect produced by nicotine.
So I have a pretty strong feeling that he is not lying about weather the L-Nicotine is the reason that this liquid is mcuh more satisfying then ALL the others I have tried...(and I have tried ALL of them)...He wasnt trying to convince me that they were stronger but more explaining WHY they effected me so much differently...Thanks
Drew
Last edited by Drewsworld; 02-26-2010 at 06:02 AM.
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Super Member
ECF Veteran
OK, not going anywhere near the chem lab stuff, LOL.
I just found out that the sample which I loved so much is now called Signature Tobacco. This stuff is just DEE-licious!!! I have difficulty describing flavors sometimes, but if I had to compare it to other tobacco flavors, I'd say it has hints of Virginia Tobacco and Kent along with something else I can't quite describe. I'm gonna be getting some of this one for sure! The one now called Plain Tobacco was also very good and very comparable to a good Marlbro flavor. I just vaped a bunch of the Menthol and for a non-menthol smoker, this stuff has a very pleasant and interesting taste. Bravo Drew, you've got some winning flavors here dude!
Thanks again for the test samples Drew, I'm looking fwd to all of the new flavors to come!
Ed
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Originally Posted by
Drewsworld
I havent tried it outside of mixing in a cart...2 drops of Signature Tobacco with about 4 drops of HV555 on top is kinda tasty on the 510HV
atty at 7.4 volts...Instant nic Buzz!!!!!
I also like another flavor that will be released shortly 2 drops with 4 Drops of Pear lung about 30 minutes before the last 2 carts of Sleepytime, gives sweet dreams without waking me up !!!!!
Well that was my thought. Adding a couple of drops of the Plain Tobacco to any and all cartos to kick them up a notch. But I'm sure that once other flavors are introduced I will find other combos.
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Well I took the bait and ordered some sample bottles.
Drew is the Spicy one the hulk flavor everyone was talking about?
Also when are you getting more 510 attys in? I had to order pink ones!
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