1 March 2010
New nicotine cigarette gives rapid lung delivery of nicotine
After tests by Health New Zealand Ltd and Christchurch Clinical Studies Trust in Christchurch NZ in 2009, this product is now ready for commercialization as a smoking substitute or as a stop smoking medicine.
SRNT 2010_ PosterAbstract_ Rose.doc
This device was tested for Duke University (the patent holders), in 2009 on nine healthy smokers. Results were announced by Principal Investigator Dr Jed Rose, of Duke University at the 16th Annual Conference of the Society for Research on Nicotine and Tobacco (SRNT), Baltimore, Maryland, USA on 27 February 2010. The inventors are Rose, his brother Dr Seth Rose, an organic chemistry professor; Dr Jim Turner, a co-inventor of the nicotine inhaler; and Dr Raju Murugesan, a pharmacologist at Duke. Dr Laugesen and Dr Chris Wynne of Christchurch Clinical Studies Trust were co-authors for this SRNT paper, entitled
Pulmonary delivery of Nicotine Pyruvate: Pharmacokinetic and Sensory Characteristics
From WebMD Health News
New Nicotine Inhaler May Help Smokers Quit
Daniel J. DeNoon
Authors and Disclosures
March 3, 2010 — A new type of smoke-free inhaler gives would-be quitters a vapor with nearly as much nicotine as a cigarette.
Nicotine replacement is one of the most effective tools for helping smokers quit, says Jed Rose, PhD, director of the Duke Center for Nicotine and Smoking Cessation Research.
"There is the patch, gum, lozenges, and the current inhaler. But none effectively satisfy a smoker's craving for the act of inhaling and feeling nicotine going into the lungs and giving that rapid boost of nicotine into the bloodstream in a user-friendly way," Rose tells WebMD.
The problem is that cigarettes are still the most efficient nicotine-delivery device ever created, says Scott McIntosh, PhD, associated director of the smoking research program at the University of Rochester, N.Y., who was not involved in the Rose project.
"It would be great to have a product that would deliver nicotine as well as a cigarette," McIntosh tells WebMD.