Chantix
Page 1 of 8 12345 ... LastLast
Results 1 to 10 of 76

Thread: Chantix

  1. #1
    PV Master ECF Veteran
    Join Date
    Jan 2008
    Location
    Port Charlotte, FL USA
    Posts
    5,623

    Default Chantix

    Feb. 2: The news for Pfizer's Chantix was not good today. The US FDA says the smoking cessation drug likely causes some users to have suicidal urges, and warnings might be necessary for the product.

    Ah, the implications. Let me first say that I had Chantix prescribed for me, paid the $165 first month's cost and consumed the entire prescribed number of pills. Every morning, the pill hit my stomach like a red-hot poker, causing pain for about two hours. Then came daily nausea. But I persisted. As for nicotine cravings ... I experienced no easing. Nothing at all. But willpower alone -- and resumption of pipe smoking -- has kept me off cigarettes for 200 days as of today, ever since I began Chantix (please don't call me a successful Chantix user!).

    Now I'll let you connect some dots.

    Last year, Johnson & Johnson paid $16.6-billion to buy Pfizer's consumer healthcare unit. At that time, this was written on a financial web site: "Pfizer’s products will give Johnson & Johnson the lead in several new categories, including mouthwash and smoking cessation." Also: "The move would add several well-known brand names to J&J's lineup, including Listerine, Nicorette, Visine, Sudafed and Neosporin."

    Pfizer produces Chantix, and the cost to purchase Pfizer's prescription division would be astronomical. But what would happen if that cost could be decreased by making the stock less valuable? And the way to do that is to scandalize or damage a big moneymaker, Chantix. That's what the FDA just did. Smokers wanting to quit will have second thoughts about seeking a drug that might cause disturbances so severe that suicide seems desirable. Pfizer profits will take a hit. The company's value as a purchase target will decline.

    And smokers will move to NRT products (which the US government actually promotes on federal Web sites with our taxpayer dollars) that will keep them addicted and buying drugs for the remainder of their life.

    J&J must be smiling. But that's the way the game is played. Follow the money. It's all about money and this smoking cessation game is like Monopoly played by high rollers only.

    I expect more bad news about Chantix in days to come. You can sense the money moving on the table as the dice roll.

  2. #2
    Full Member
    Join Date
    Jan 2008
    Posts
    91

    Default Re: Chantix

    I took Chantix (champix in the UK) and it worked for me while I was taking it BUT when I stopped it after 3 months as directed I experienced the worst black detression imaginable. Never in my life had I had depression, just the normal ups and downs of life but that drug, or the absence of it, made me literally feel suicidal. At the time no-one could help so I joined a Chantix forum. I reckon 20% of the people there had very real problems with severe depression. Now, in the UK there are frequent reports in the news about suicidal thoughts with Champix. These people have my sincerest sympathy. My guess is that when the drug is stopped, and the nicotine receptors no longer have Champix bound to them and there is no nicotine around either, that for a period of several weeks it is impossible to feel pleasure of any description. Stress of any sort, therefore, becomes intolerable. In my opinion Champix should be banned. Better to smoke than be dead from suicide. It took me many weeks to recover and even the memory of that time makes me shudder. Please believe that these side effects are very much for real.

  3. #3
    PV Master ECF Veteran
    Join Date
    Jan 2008
    Location
    Port Charlotte, FL USA
    Posts
    5,623

    Default Re: Chantix

    Woody, I'm glad you made it through that ordeal.

    After Chantix failed to decrease my smoking urges, I became somewhat depressed, but nothing like what you describe. I blamed my feelings on not smoking, rather than the drug. Cold turkey quitting has driven me almost insane in the past, before I returned to smoking. I had to have nicotine to settle my system!

    What Chantix is supposed to do is block nicotine receptors in the brain. With receptors blocked, nicotine has no pleasurable effect. Without Chantix, when smoke is inhaled, nicotine travels from the lungs through the blood to the brain and is processed there, resulting in the release of the natural hormones serotonin and dopamine. Those two chemicals explain how we can be both calmed and picked up by nicotine. But the Chantix cuts those chemicals short -- in all instances. These are the "pleasure" centers of the brain we're talking about disabling. And there's talk now that Chantix could work for alcoholics and those addicted to other drugs. How? No pleasure. Why use?

    But things that normally trigger a pleasant response, like food or sex, are also crippled by Chantix. If those are important to you, it's easy to see how suicidal thoughts of life not being worth living might take over. Nothing makes you feel pleasure. And you're paying $165 a month to be a numb zombie. If tobacco is the devil's weed, Chantix might just be the devil's drug. Beware any other drug, or vaccine to come, that works in a similar fashion and promises freedom from addiction. The price might be more than most want to pay.

  4. #4
    Full Member
    Join Date
    Jan 2008
    Posts
    91

    Default Re: Chantix

    Chantix seems to effect everyone differently. Whilst on it I felt full of energy and apart from missing smoking my mood was great. Some folks on the forum that I joined actually wanted to stay on it forever. Coming off it was the problem. Brain drugs tread on dangerous ground. My big worry at the time was that the effect of depression was going to be permanent. Thankfully I was wrong

  5. #5
    ECF Founder Verified Member
    ECF Veteran
    Supporting Member
    SmokeyJoe's Avatar
    Join Date
    Dec 2007
    Location
    United Kingdom
    Posts
    3,527
    Blog Entries
    1

    Default Re: Chantix

    Out of interest, Woody, did you ever manage to quit nicotine "cold turkey?" If so did you suffer any depression when you did so?

    I heard that it is quite a common and underreported symptom of nicotine withdrawal.

    Regards,
    SJ

  6. #6
    Full Member
    Join Date
    Jan 2008
    Posts
    91

    Default Re: Chantix

    Not cold turkey exactly SJ, but I have withdrawn from NRT as directed in the past. Certainly I noticed feeling somewhat down but it wasn't the same kind of reaction as Champix withdrawal. In the end I came of Champix by cutting the pills in half and then quarters and so on and on each reduction waves of black depression would hit about 36 hours later. This could even wake me during the night with a feeling of dread like nothing I have ever experienced. On the forum I was taking part in some of the people had total breakdowns and it became accepted that a VERY slow withdrawal was the only way. Oddly, others felt lousy on it and then felt huge relief when they stopped it.
    My theory is that Champis binds to nicotine receptors 24/7 unlike cigarettes and when removed abruptly is a massive shock to the system. Interestingly though, cravings did not increase for nicotine. NEVER AGAIN

  7. #7
    Ultra Member Verified Member
    ECF Veteran
    Supporting Member

    Join Date
    Jun 2008
    Location
    USA
    Posts
    1,273

    Default Re: Chantix

    We know the behavior of the receptors isn't the same in everyone or we would all have the same addiction habits and level with the same products at the same point of use. I recently read a summary of a medical paper about Chantix binding to receptors that haven't yet been "activated" by nicotine in some/many people, and this causing many of the side effects, particularly the common nausea (just like when you first smoked and some receptors were hit with nicotine, or when you overindulge with cigs). In addition to those effects upon taking the Chantix, now the Chantix is training ADDITIONAL receptors to expect nicotine. It would make sense then, that when the Chantix use dimishes or stops those new receptors behave unpredictably, along with whatever happens with the receptors that were already activated as part of the addiction.

    I called the Chantix line recently with some dosage questions (that they couldn't answer), and before hanging up was requested to listen to their new warning which included "Avoid driving while using Chantix".

  8. #8
    Full Member
    Join Date
    Jan 2008
    Posts
    91

    Default Re: Chantix

    I recommend avoiding Champix/Chantix at all costs. Recent suicides in the UK have been attributed to withdrawal from Champix. That is one side effect that is not listed on the pack. You would be better off smoking. |It might save your life!

  9. #9
    ECF Founder Verified Member
    ECF Veteran
    Supporting Member
    SmokeyJoe's Avatar
    Join Date
    Dec 2007
    Location
    United Kingdom
    Posts
    3,527
    Blog Entries
    1

    Default Re: Chantix

    On a note slightly tangential to the topic but related to Bob's "follow the money" observations, it has been noted by some that the release of data showing the lack of effectiveness of antidepressants in most users neatly coincides with the fact that a whole class of drugs, antipsychotics, are being re-packaged as antidepressants.

    Some believe that this has been entirely instigated by the pharmaceutical companies who, of course, produce both classes of drugs.

    SJ

  10. #10
    Full Member ECF Veteran
    Join Date
    May 2008
    Location
    Cleveland Ohio... the mistake on the lake;-)>
    Posts
    116

    Default Re: Chantix

    more good news....

    My wife used to work in big Pharma. As a result she still receives email updates from the big drug companies and the FDA.

    She just received a warning (i believe from the FDA)regarding an elevated risk for sudden onset heart attacks within Chantix patients... supposedly it is messing up the heart rhythm for some people.

    Evil Drug

    Stay away!!!! :o

Page 1 of 8 12345 ... LastLast

Tags for this Thread

Bookmarks