Questions about Nicotine..

[Kate]

I was reading on another thread that nicotine is better absorbed in an alkaline environment and was wondering if anyone knows about the acidity of our vapour?

A while back I came across something that said propylene glycol and/or glycerine produce alkaline vapour but I can't find that information again and am beginning to wonder if it's true.

If esmoking vapour is alkaline then it would be definitely good for teeth, it would neutralise acid and allow them more time to remineralise. It would also mean that we absorb even more nicotine in comparison to cigarettes than current like for like, mg for mg, calculations suggest.

[jimldk]

I was reading on another thread that nicotine is better absorbed in an alkaline environment and was wondering if anyone knows about the acidity of our vapour?

A while back I came across something that said propylene glycol and/or glycerine produce alkaline vapour but I can't find that information again and am beginning to wonder if it's true.

If esmoking vapour is alkaline then it would be definitely good for teeth, it would neutralise acid and allow them more time to remineralise. It would also mean that we absorb even more nicotine in comparison to cigarettes than current like for like, mg for mg, calculations suggest.

Hi kate...my litmus test shows it to be alkaline in nature with reading from pH 7.8 to 8.5...highest found in E-liquids from E-cig and lowest from Ruyan cart samples...
Incidentally, the fishy / urea smell that found in spoiled samples(which I had some ) is acidic ranging from 6.2 to 6.8....those spoiled sample does not give much vapour..most likely the PG has been oxidised??...still not sure yet but still being investigated...

Hope this info helps....

[Kate]

That does help, many thanks Dr Loi.

It's certainly food for thought that we might be absorbing nicotine more efficiently than with cigarettes.

I'll be interested if you discover anything more about the spoiled juice, some people have mentioned bad tastes like that so it might be common enough for concern.

[spufmonkey]

Hi everyone Nicotine, is extremely good for you!..don't listen to old people like Kate or Tropical looser..there just treated the wrong way. If Nicotine is so bad, why do they sell it in stores? thank you everyone have a nice day. happy smoking

i can see a ban coming someone's way soon!

[shawnp1]

indeed i just banned him. sorry for all the problems. all the posts he has made are deleted that i found. please report any others an i will take care of them also. sorry about that kate, an tb some people are just that way.

[TropicalBob]

Yes, your action is appreciated. Lord knows, we have real issues to discuss. Thanks ShawnP1.

[Kate]

Schematic diagram showing rise in venous blood nicotine levels after smoking a cigarette and after using different nicotine replacement therapy products, following overnight abstinence from cigarettes

RCP | Nicotine Addiction in Britain

I found this interesting, it shows that the spike in blood nicotine levels after smoking is much more pronounced than with NRT. That might be one of the effects we crave when quitting tobacco. It would be useful if we could compare nicotine levels from esmoking, I suspect it would be more like smoking than NRT because of absorption via lungs.

"Since no current nicotine replacement therapy (NRT) formulation uses the pulmonary route of absorption, none can mimic either the extremely high and rapidly acquired arterial nicotine concentrations which occur when tobacco products are inhaled, or the rapid pharmacological effect that this produces. The typical time course of the increase in nicotine levels in venous blood after smoking a cigarette is also faster than after most nicotine replacement products ..."

[dc2k08]

There was a variant gene discovered recently that is said to be found in some people and makes it more difficult for them to quit nicotine:

Penn research probes genetic underpinnings of nicotine addiction


That test would be interesting kate, i wish we could get someone to do it.

[TropicalBob]

DC, I had read that .. and it gives new relevance to the claim that "I'm a born smoker." Yes, some might be, and quitting will be far harder or impossible if it's "in your genes."

Kate, e-smoking should be closer to cigarette smoking than any NRT method. But, sorry to report that I do not get that instant kick a cigarette provided 17 months ago. If fact, I rarely feel anything except maybe a burning in my throat (unwelcome). I find that nasal snuff is close to the fast-acting nasal spray from Big Pharma. Snus and pipes and cigars are way down the list -- in that "30 minutes to feel" territory.

I've not tried any liquid stronger than 24mg -- and that didn't satisfy me. I look forward to trying something that delivers -- per inhalation -- exactly the nicotine content I once got from a premium cigarette. E-smoking's vapor is great; the taste is better than tobacco; but the impact is most important, and is far too delayed for me. Given that we're providing nicotine a lung route to the brain, I can't figure out what is missing with e-smoking. But something is.

[ZambucaLu]

TB,

I think what you said on another thread made a lot of sense:

"And the vapor lacks a few things, we've learned, that contribute to the "satisfaction" smokers swear by with real cigs. No carbon monoxide, for instance, because no combustion is taking place. No harmine, an important chemical that prolongs the pleasurable impact of your brain's release of serotonin and dopamine. Nicotine triggers the release of those "feel good" chemicals, but with e-smoking, the pleasure does not last. As a consequence, we suck and suck and suck on e-devices, trying to recapture the good feeling that is so fleeting."

Something is missing....even if it's a "bad" something. I also have not felt satisfied enough to quit the analogs. I have tried the 24mg...now I'm waiting on the 36.

And I could believe that "it's in the genes". My mother is 87 and still smoking strong (with no associated breathing problems to boot). My oldest brother (who can afford it), has tried everything from gum to acupuncture to hypnosis....nothing lasts.

I knocked off about 2 packs a day with the ecig...I still smoke 10-20 a day, which I just can't seem to kick. Maybe the 36mg will make a difference...maybe not. But I LOVE not smoking more than a pack of analogs a day....that's quite an achievement for me. And I remain hopeful that it will get even better in time

Lu