10-30-2009, 03:22 AM
10-30-2009, 03:42 AM
10-30-2009, 04:36 AM
Yea, I get a little confused too sometimes about what I'm saying.
Originally Posted by ladybug
10-30-2009, 08:52 AM
Now that's starting to fit. Goes a long way towards explaining the different reactions we're getting with e-cigs. I fit in with the last paragraph.
Originally Posted by DVap
This could go a long ways towards getting people off the cigs and on to reduced harm products. A bit more pragmatic then the one size fits all, but it may just work.
Last edited by Stubby; 10-30-2009 at 09:33 AM.
10-30-2009, 04:43 PM
Great concept DVap! I was not aware of MAOI's in tobacco. I had referred previously to tobacco have something addictive more than nicotine, due to my craving a hit when drunk. Even though I know that hit will taste like trash.
10-30-2009, 05:49 PM
This has been a very interesting thread to read, and has given me a little bit of insight into my newly acquired vaping habits. When using my e-cig, I'm always getting some minute part of the liquid directly on my lips, and I feel the nicotine fuzziness I used to experience when I would chew the gum. When using the stronger 36mg juice, I notice this a lot, and I like it A LOT. When I use some of the flavored juices, that come in the 24mg strengths, I don't notice this effect nearly as much, and I vape them constantly. The 36mg does give me a better hit, and allows me to put down the e-cig for a bit (unless I am drinking alcohol, in which case I keep a battery charging constantly).
That being said, I also have an e-pipe (des601) and it's high strength cartridges are labeled 18Mg, and are somewhat maple flavored. I get an awesome enjoyment out of them, I get a good hit, and feel relaxed from using the pipe. I still don't want to put it down. When I refill it with the 36mg e-juice, I still get a nice hit, but it's not as relaxing as the 18 mg pipe juice. I know the pipe cartridges are coming from a difference source than the regular e juice, so I am under the opinion as others have said that all juice is not created equal.
10-30-2009, 10:33 PM
Interesting to note:
Here's something from the National Institute on Drug Abuse.
You'll notice a myopic focus on nicotine. The M.D.'s and Ph.D's go on and on with not a hint of any other factor being considered, even tangentially, in tobacco addiction.
Do we know something they don't, or have they drunken too deeply of the kool-aid?
Last edited by DVap; 10-30-2009 at 10:55 PM.
10-31-2009, 04:06 AM
I had a lengthy discussion with Kin earlier about MAOIs in tobacco. This is the thread:
Certainly was interesting read! I think the MAOIs are my Achiles heel. I am having to rethink my strategy!
10-31-2009, 04:24 AM
I'm not sure if this has been brought up before or if there's any validity to it - but are all 'analogues' more or less made with the same additives from one manufacturer to the next? (or even from brand to brand from the same manufacturer?)
- Is there any possibility that those having a harder time with nicotine replacements may be 'missing' other ingredients that other analogue smokers may have not come in contact with, or at different levels?
And while I don't know a darn thing about chemistry or how nicotine interacts with the body - is there any chance that any of these other ingredients may effect the speed at which nicotine is absorbed/dissipated in/from the bloodstream that may account for the differences in nic levels during blood tests?
My apologies if either question's been answered/tested, but as someone who's having a bit of a hard time with the transition this is an interesting thread
10-31-2009, 05:06 AM
I believe that MAOI's in tobacco come from the tobacco itself. Just as different tobacco varieties have more or less nicotine, it is reasonable to expect that different tobacco varieties also have more or less MAOI's. The nicotine content of tobacco is what gets all the attention, we know how much nicotine we get from an analog, it's tested and reported. Testing/reporting of tobacco MAOI's, on the other hand, is pretty much nonexistent.
Originally Posted by Thumbscrew
Nicotine itself enters the blood via the mouth, respiratory tract, and lungs. I have trouble seeing how co-factors can modify the mechanics of absorption. Something that must be considered is that nicotine is quoted as having a half-life of 2 hours... but this is an average. Some individuals may metabolize it much faster or much slower. Now the hard part is what happens on the brain side of the blood/brain barrier... do MAOI's work to potentiate nicotine, or do they work independent of nicotine? Dunno.
If you're vaping 36 mg, and you're still going crazy, you've got an issue other than nicotine, and MAOI's are currently the prime suspect.
Last edited by DVap; 10-31-2009 at 05:13 AM.