So - are we getting it or are we not - nicotine

[IANAN]

(Passion Flower) Day one

1. Desire to smoke- Nice even day with little or no desire to smoke, especially in the afternoon. Period of 3 hours without any craves at all

2. Mental Awareness state (Mental Fog)- Different type of fog later in the day.

3. Anxiety (Relaxed state) and restlessness- Slept normally the night before. Lots of energy - different than Cat's Claw energy or coffee- best described as a more mellow energy.

4. Perceived GI (Gastro-intestinal) effects including effects on bowl movements- odd effects later in the day.

5. Effectiveness of and frequency of vaping sessions to reduce cravings- Still most effective when drinking coffee .

6. Number of traditional cigarettes consumed (If any)- 11

Twisted....You mean it rains in the US Northwest -- I would have never guessed that ....

[a2dcovert]

My GP put me on a new anti-anxiety drug, Pristiq, to see if we can calm down the situation. In my past two attempts to quit smoking it was obvious that the lack of cigarettes caused a chemical imbalance. My personality took a 180 degree turn. My normal personality is a calm even tempered persona. I am usually very slow to anger and totally in charge of my emotions. Right now and in the 2 previous episodes I developed a very quick temper and was subject to rage if pushed too far. This to me is the scariest part to me.

The bad part of this quest to find the truth is that the medical community will go to great lengths to avoid proof that treatment for chemical imbalances can push the individual to the point of uncontrolable rage. Chemical imbalances whether influenced by natural events can also be caused by treatment with the wrong type of chemical. My theory is that something in cigarette smoke acts on the brain chemistry and the brain becomes dependant on this chemical. Lack of this chemical will result in an imbalance.

This is why the identification of this chemical is so important to me. If I can't be treated to reverse the imbalance I will have to return to smoking. I will once again have to make the decission of quality of life over quantity. It really is that simple.

Kevin

[DVap]

This thread looks like it's becoming a trash-can thread for multiple lines of inquiry that might benefit from being spun off.

Any thoughts from anybody about taking whole tobacco alkaloids to one thread, herbal alternates to another, and trace level tobacco psychoactives to another?

[IANAN]

My theory is that something in cigarette smoke acts on the brain chemistry and the brain becomes dependant on this chemical. Lack of this chemical will result in an imbalance.

This is why the identification of this chemical is so important to me. If I can't be treated to reverse the imbalance I will have to return to smoking. I will once again have to make the decission of quality of life over quantity. It really is that simple.

Kevin

Kevin,

Anabasine, Anatabine, Myosmine, Cotinine, Harman and Norharman have had animal studies done that would support they are involved in additional reinforcement of the nicotine.

Nornicotine and Acetaldehyde also have animal studies done that would suggest additive and/or synergistic effects with nicotine but both are very likely carcinogens also based on animal and human data.

Antabasine, Anatabine, Harman, Norharman, and Acetaldehyde all are known to effect MOA inhibition. The beta-carbolines and Acetaldhyde also effect serotonin production. Beta-carbolines also allow other alkaloids to do things they normally wouldn't (Potentiating effect)...

When we aren't talking about chocolate covered chilis in this thread we have been digging up research into what could be missing and how to just extract that or dietary substances/additives to e-liquid that could replicate or replace what is missing . Lots and lots of research concentrated just in this here thread ....


There also more-or less are instructions on how to make your own tobacco extracts- but be very careful with that.

[IANAN]

This thread looks like it's becoming a trash-can thread for multiple lines of inquiry that might benefit from being spun off.

Any thoughts from anybody about taking whole tobacco alkaloids to one thread, herbal alternates to another, and trace level tobacco psychoactives to another?

We need like our own subforum.... baring that three sticky threads if the moderators are around and listening would probably do the trick... but preserve the research in this one.... so much lit review in one spot....

[DVap]

Agreed that research, theory, and speculation don't have their own home here... and they need one.

[a2dcovert]

Sorry for cluttering up your thread. I thought this was for persons with real life problems seeking solutions.

[kinabaloo]

... My theory is that something in cigarette smoke acts on the brain chemistry and the brain becomes dependant on this chemical. Lack of this chemical will result in an imbalance.

This is why the identification of this chemical is so important to me. If I can't be treated to reverse the imbalance I will have to return to smoking. I will once again have to make the decission of quality of life over quantity. It really is that simple.

Kevin

It's been touched on many times and is worth stating explicitly: to what extent does smoking create an imbalance not just temporarily, fixed with another smoke, but permanently (at least for some people); and to what extent was there (again, for some people) a pre-existing imbalance that smoking (or vaping something like WTA, or even some other med / herb / diet) helps to improve (redress or make bearable)? It's a big question.

[IANAN]

Sorry for cluttering up your thread. I thought this was for persons with real life problems seeking solutions.

Nah we aren't mad at you or anything... Several have noted that this thread is past 700+ posts and is a little unwieldy at the moment. There is so much research and so many links to studies in the 700+ posts though.... We need to find a home for all this info.

[kinabaloo]

DVap - The OP is apparently temprarily banned atm. I like this thread as it is because it creates new ideas by bringing together different themes.

But you and Exo could do well to take the test part 2 to a new thread, while this continues as a well-spring ...