"A Primer of Drug Addiction" Good info about nicotine

[h8isgr8]

I stumbled across an old book that contains some good info about nicotine and cigarettes. It's a little dated, but good info none the less.

The best piece of info I gleaned from the book is the fact that only around 20% of the nicotine in a cigarette is actually absorbed. I have been looking for this number for quite some time.

The nicotine section starts on the bottom of page 151 and continues to the end of the book.

A primer of drug action: a concise ... - Google Books

[DVap]

I stumbled across an old book that contains some good info about nicotine and cigarettes. It's a little dated, but good info none the less. The best piece of info I gleaned from the book is the fact that only around 20% of the nicotine in a cigarette is actually absorbed. I have been looking for this number for quite some time. The nicotine section starts on the bottom of page 151 and continues to the end of the book. A primer of drug action: a concise ... - Google Books

10% is oft quoted, so 20% is on the high side, but in the ballpark.

Those google book results don't work when passed as a second hand link... at least they don't for me.

[h8isgr8]

The link works fine for me on IE and FireFox.

[olderthandirt]

Well, the link worked for me. Neat little book.

The chapter on caffiene and nicotine pretty much mirrors what has been discussed here the past few months with respect to the pharmacology of nic, relationship twixt the severity of the addiction and depression, the difficulties in stopping smoking but...

It is just that, a primer.
No discussion of MAOI's in tobacco and their role in either the addiction or cessation aspects.

Cessation therapy is the same old crap regarding currently recognized nicotine only NRT approaches.

Nice little find for sure but, lacking

[Vocalek]

I found the description of the nicotine inhalor interesting. The device does not deliver nicotine to the lungs. The nicotine is deposited on the buccal mucosa (lining of the mouth) from where it is absorbed. So the dynamics more closely resembles how you get nicotine from the gum or lozenges.

Each inhaler contains 300 doses (0.016 mg of nicotine per puff). I had a coworker who participated in the clinical trials, and she told me that you need to use up the liquid within 20 minutes. Can you imagine taking 300 puffs in 20 minutes? No wonder nobody ever gets the full 10 mg. of nicotine out of one inhalor cartridge.

The author noted that while the action mimics some of the behavioral features of smoking, but does not vastly improve quit rates.

[Darmeen]

I found the description of the nicotine inhalor interesting. The device does not deliver nicotine to the lungs. The nicotine is deposited on the buccal mucosa (lining of the mouth) from where it is absorbed.

I read somewhere on here that the nicotine that we get from our pv's is similar to that, and that it is not the lungs that absorb the nicotine from the PV.

I wish I could remember which thread I read that in...Hopefully someone will come in here that can remember better than I.