Tweaking the nicotine

[warp1900]

liscab, you and your "not wired for addiction" brain.

I think the point that I failed to state succinctly in my previous post was this:

"Some brains are wired for addiction, some aren't".

Now habits.. habits are a whole other thing.

Very interesting Dvap, but I am addicted to making mods, lol.

Seriously, you may have a very good point there.


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[stevo_tdo]

I find it interesting that some of the heaviest and most addicted smokers (the ones who go crazy the moment they run out of smokes) are in the group who have dopamine related disorders.

Read up on bipolars and/or schizophrenics and smoking, the correlation is very high. Both share a disorder that affects dopamine as a neurotransmitter in the brain.

So a reasonable hypothesis might be that in addition to the action of nicotine on the nicotinic acetylcholine receptors in the brain, the dopamine system is also modified by smoking to a greater degree in some individuals than others. The very high smoking rates in the bipolar/schizophrenic groups perhaps demonstrate this more at the extreme.

Hit the nail on the head there. I have all ready come to terms with the fact that I need nicotine to function. (I have schizophrenia) You should be around me when I go no nic.

Before the onset of the disorder I could go months without smoking. But after my symptoms became pronounced I could not.

I really wish the Fda would see the benefits of the E-cig. Think of the financial burden on health care, why compound the large cost of psychiatric care with the possible higher cost of cancer treatments due to smoking in the mentally ill?

[kinabaloo]

I really wish the Fda would see the benefits of the E-cig. Think of the financial burden on health care, why compound the large cost of psychiatric care with the possible higher cost of cancer treatments due to smoking in the mentally ill?

From those indistries perspectives, the 'financial burden' is a fantastic money-spinner.

[DVap]

Hit the nail on the head there. I have all ready come to terms with the fact that I need nicotine to function. (I have schizophrenia) You should be around me when I go no nic.

Before the onset of the disorder I could go months without smoking. But after my symptoms became pronounced I could not.

I really wish the Fda would see the benefits of the E-cig. Think of the financial burden on health care, why compound the large cost of psychiatric care with the possible higher cost of cancer treatments due to smoking in the mentally ill?

I should say here that I'm not suggesting that everyone who is hooked hard on cigarettes has a dopamine disorder. Things functions on a continuum, and in addition to both poles (those who can smoke casually and put them down just as easily -vs- those who must have their cigarettes and can't tolerate being without them). Perhaps the truth is that the domamine reward system in some people is just quite resistant to being tweaked by nicotine, while in others, it is very susceptible to being tweaked by nicotine.

[kinabaloo]

I should say here that I'm not suggesting that everyone who is hooked hard on cigarettes has a dopamine disorder. Things functions on a continuum, and in addition to both poles (those who can smoke casually and put them down just as easily -vs- those who must have their cigarettes and can't tolerate being without them). Perhaps the truth is that the domamine reward system in some people is just quite resistant to being tweaked by nicotine, while in others, it is very susceptible to being tweaked by nicotine.

Suseptibility to addiction to nicotine is not equivalent to the less ideal dopamine system; it could be quite the opposite. That being addicted to nic id not a good thing in no way implies that the sytem that can get addicted is the inferior one.

There are people who are relatively unmoved by anything much, have little sense of humor and are, well, dull and machine-like. Seat me with the 'smokers'. Not getting mad at this world sometimes is the crazy state of mind.

[kinabaloo]

Very interesting Dvap, but I am addicted to making mods, lol.
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It's a desire not only to make things, but to make things better.

[Liscab]

I think that if I created a liquid ,let's say with tobacco absolute that is suppose to have not nicotine but it could smell like tobbaco, and add some flavor and some quemical to give you a hit and I tell you it is 36mg nic and you like it, you are gonna believe me and you are gonna go on without nic I would be cheating your brain and your adition

[kinabaloo]

That might work for some people

It's not all placebo, nicotine does have some physiological effects, even without the co-conspiritors found in smoke.