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Blog entries by kinabaloo

  1. DVap, in his blog, states that a NET is not an impure WTA. That's odd because WTA stands for 'Whole Tobacco Alkaloids' meaning all the alkaloids in tobacco, not just nicotine. The acronym is not PureWTA (PWTA). The attempt to redefine the term does look a lot like it is being treated as a...
  2. DVap - The history behind WTA. which you have written me out of, said that the problem with traditional NRTs, including vaping, was that it dide not take into account the full spectrum of alkaloids. Purity is a different matter. A NET is a WTA, no question. You are redefing WTA as a OTA (Only...
  3. Suggested simple improvent to the cold ethanol method The idea is to mix some sodium carbonate powder (USP / made from food-grade sodium bicarbonate by heating the powder in an oven) with the tobacco before adding the alcohol (immediately after - no need to wait); this should free-base the...
  4. The ~1mg / g nicotine content listed on cigarettes / tobacco is that received from the smoke. There's ~10x more than that available in the tobacco for extraction (~1%). If I am right that vaping is more mist than vapor, some fraction of the alkaloid salts would be inhaled; but what 'benefit'...
  5. In summary on cotinine and niacin - cotinine might be the main benefit giving constituent, and minus the negatives of nicotine (e.g increaded heart rate), with niacin as the MAOI component. Steeped e-liquid more like WTA (though not it's equal, maybe not too far off?) That some nicotine will...
  6. "Nicotinamide, a form of the B vitamin niacin, is known to exert similar effects on the brain as benzodiazapenes.13 Nicotinamide stimulates the GABA-benzodiazapene receptor complex, an inhibitory neuron grouping. By activating these neurons, a calming effect is the end result.14 Other...
  7. Thinking about the relative nature of smoke and vapor. Smoke will contain other alkaloids beside nicotine, but what nicotine is released is more likely to be oxidised than the nicotine in vapor (because largely the 'vapor' is mostly actually a mist of tiny droplets of PG/VG with the nicotine...
  8. One wonders about the anecdotal evidence regarding the advantages of: 1) 'steeping' and 2) high power vaping - and whether there might be psychopharmacological advantages to oxidation / heat induced changes (beyond improvements in taste). This paper is interesting :...
  9. I would be interested to know if the simple combination of nicotine and anatabine*, in appropriate ratio, would be as effective as WTA (possibly even beter). The obvious omission being the more minor harmala alkaloids that have some reasons to be thought possibly important. On the other hand,...
  10. Indeed, harm reduction is about efficacy (effective, safer alternative one doesn't need to over-use) and that includes satation - which needs include a 'hit'; as you said, even the WTA if weakened sufficientlt by a bad device will not create that impact + satiation. Ride a roller and the buxx...
  11. People may wonder just what is the difference between WTA and nic-only e-liquid. And note that this only applies to those who 'need' it. A few analogies come to mind ... If one buys a atandard bar of chocolate one can ('must' even) much the whole lot in one go; whereas a high quality...
  12. Although one could sort-of have a nicotine-free WTA, it would no longer be WTA ! Only a small fraction of the alkaloids in tobacco make it into the body when smoking; a lot is just combusted as it can't vaporise/escape from the matrix. The profile of alkaloids in smoke will be somewhat...
  13. Indeed, it is not the nicotine that causes the symptoms, but as I have been saying, 'the use of nicotine-alone'. I think I see the confusion now; to be absolutely clear - it is the absence of the other alkaloids that can lead, in some people, to these symptoms, not the nicotine itself. However,...
  14. Third and last time to give you the same reply - I never said 'will' I said 'could'. I'm talking about those for whom nicotine alone does not satiate and who actually need WTA because that is what they have been used to. For perhaps decades these people have been absorbing the full range of...
  15. Things will hopefully change in time, but while the majority are unaware of the issues and the majority here are the minority for whom nicotine-alone works, the big picture will barely change. Current (non-WTA) e-liquid is a failure, with a sucess rate of only around 25%. That might be twice as...
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