I let my xc soak for as long as it takes to put the drip tip back on and put the mod in my face. This stuff is amazing.
I second the keep it simple comment, and the air hole needs to be positioned just right, so the incoming air passes right over the coil.
The best setup for an IGO it's what works for you with what wick and coil materials you have, what kind of device you're connecting it to, and your preferred type of vape. I'd compare your question to: "what's your favorite juice?"
That said, I'd recommend ditching the mesh. If you're using a mechanical mod then I'd recommend shooting for about .8ohm. If you don't have any I'd recommend you order some xc-116 and use your silica in the meantime.
I just wrapped up a 1.1 ohm coil with .8mm ribbon. Ended up higher res than I expected so I'll try one less wrap next time. Still hits like Debo though.