I'd give two strands of 26 gauge and two strands of 30 gauge wire a shot if you want to stick with four wires. A four-strand 30 gauge coil at ~0.3 ohms is a bit on the "hot" side for 50 watts. Or you can bump it up to around 0.5 ohms and four strands of 30 gauge should work well at 50 watts.
While it doesn't support mixed gauges, the
Steam Engine calculator will definitely help you out. Select "Round, twisted/parallel" under "Material and profile" and play around with the numbers. The calculated values for heat flux and heat capacity will help give you an idea of how hot the vape will be, and how fast the coil will heat up and cool down. Be sure to change the wattage value for heat flux to 50 watts (or whatever wattage you intend to use the coil at). I like to keep the heat flux under 300 mW/mm^2 and the heat capacity under 150 mJ/K for coils around 50 watts -- those numbers give a very warm (but not too hot) vape and don't have an excessively long ramp-up time. Of course everyone's preferences differ, but you'll learn pretty quickly what works best for you.
For comparison, your 0.27 ohm, 4-strand 26 gauge coil has a very low heat flux of 102 mW/mm^2 at 50 watts, which is why it isn't working well at 50 watts.