The one you need to watch for is putting the mod down on its side against something conductive, eg chucking your keys ontop of it and you bridge the circuit from anywhere on the outside of the atty to anywhere on the mod, the coil won't save you on this and your batteries will continue to drain and most prob explode.
If the screw from your button or the collar that contacts the button to the 510 come loose and you get unlucky and they bridge then it will more than likely kill your coil's and stop firing without continuing to drain and explode.
I'm making it sound really dangerous but i've never had anything come loose and have only tapped say tweezers, the topcap or a mandrel across the atty and the mod's body which will give a little spark warning you not to do it again
You can leave the batteries in the mod and undo the negative screws to them easy enough if you carry a little flathead screwdriver out and about with you, i wouldnt like to be in a situation where im out and cant disable it or say one of the negative's go a little loose, things like this never seem to happen when your sat at home next to all your screwdrivers lol