Oh a huge difference. When the RX200 is working right, it is beautiful. I have two myself and I kind of wish I never bought them. Just do a search for RX200 problem and you will get an earful. I also have two Reuleaux DNA200 (and other DNA200 mods). No problems like its sibling RX200 (except the same 510 connection). No tiny screen, balance charging works, doesn't overheat, doesn't drain one battery more, one year warranty on the DNA200 board, doesn't stop working with SS TC, doesn't just stop working like the RX200 does for some, etc.