Just a basic single subohm coil. Just curious to know what the difference is using a single thick wire compared to parallel thinner wires...
Yes, there's a difference... and that is mass/heat capacity, as well as wattage for a desired heat flux.
Using ZoiDman's 60 watts and 0.2Ω as points of reference, your net mass is 663.391 mg with a heat capacity of 305.16 mJ K-1. It's the mass that is creating a ridiculously high heat capacity. Heat capacity is a value of time-to-temperature.
If you don't mind waiting while the battery discharges for an excessive amount of time, in an effort to heat the coil to the desired heat flux value... then go for it. ;-)
Were you to drop down to say, 24 gauge, dual parallel build with the same power and resistance parameters... mass drops to 82.095 mg and heat capacity to a much faster 37.76 mJ K-1.
You'll also note that heat flux nearly doubles, from 164 mW/mm² to a much warmer 331 mW/mm². To obtain a similar heat flux, only one half the wattage is required. Something to consider if you have a APV with a "modest" wattage upper limit.
The only advantage a 18 gauge single has over a 24 dual parallel is surface area... with 349.01 mm² being over 4 times that of the 24 gauge 82.57 mm².
What I've offered above doesn't necessarily represent an optimum build, but you can certainly see that an "optimal build" is a balance of factors... rather than a preponderance of one or two factors, at the ignorance of all others.
Click my second sigline to better understand build optimization.