No different in terms of vape quality. It is bigger and heavier than 18650, this difference is really significant, it will surely give u bigger bicep. The downside is, battery is not readily available but most of the battery has larger mAh which leads to longer vape time before noticing drop in vape quality.
It is good to have 1 in collection but if you are starter, i suggest to stick to copper 18650 mod with VTC5.