The answer to your question depends.... If the size and number of batteries is fixed, a switching buck regulator will be more efficient than the booster, which will be more efficient than a linear buck. On the other hand, if you're choosing between 2 small batteries vs. 1 large one (2 CR2's or CR123's vs. a single 18650, for example), the higher effective energy density of a larger cell moves things well in favor of the booster. The only advantage of a linear buck and two small cells is simplicity, you don't need as complicated a circuit or casing design.
I'm not sure what you mean about series or parallel? Do you mean parallel Li-Ions vs. series NiMH? That's mostly a matter of how you connect the contacts in the battery case.
The datasheet for the 4050C gives the info on how to set output to a voltage other than 5V, although in many cases the 12W power limit will kick in (510's at 6V, for example), and it also seems to move the capacitors from optional to mandatory.
--Dave
I'm not sure what you mean about series or parallel? Do you mean parallel Li-Ions vs. series NiMH? That's mostly a matter of how you connect the contacts in the battery case.
The datasheet for the 4050C gives the info on how to set output to a voltage other than 5V, although in many cases the 12W power limit will kick in (510's at 6V, for example), and it also seems to move the capacitors from optional to mandatory.
--Dave