I would never recommend someone use 100mg directly to make their mixes! It's too dangerous and if you get some on you you're going to get pretty sick, if you get some on a kid or pet they could die. It isn't worth the risk if you have either in your home. I've been doing DIY for 2 years and it still scares me to use 100mg and I seldom do...only to add nic to a mix where I don't want to lose the flavor. I buy my nic in 48mg and syringe it out of the bottle. I mark my plastic bottles with a dot into 4ths using a magic marker and fill to the first mark with nicotine...that gives me a final level of 12mg. I then add my VG so I'll be at 75%PG/25%VG to the second mark. I use a glass flask to measure my flavorings and dump them in the bottle and fill the remainder with PG. Recipes I've made for a long time I don't need to measure any more and just use the bottle to measure not using the flask. But I don't have complex tobacco flavors to worry about the exact measurements. Most of my dessert flavors don't have to be down to the exact drop to taste just as good and I like to keep it simple.
Anyone new to DIY please read the stickies, especially on the safe handling of nicotine. It's highly recommended you start with a lower concentration until you feel comfortable working with it. All we need is someone spilling 100mg on them and ending up in the ER or dead and the anti-vaping people would have a field day. I started at 36mg and stayed there for quite a while. Back then the experts would have been alarmed to read about newbies using 100mg and I cringe when I see it now.
Oh sweetie, believe me, I've read all the stickies and then some! When I work with 100mg nic (I have since started purchasing 36mg btw) I make sure
1. it's a time of day that everyone else in the house is quiet. Dogs are sleeping, husband too probably lol!
2. I've got NOTHING else going on and can relax and finish the task uninterupted!
3. My mind is clear...I'm not tired, distracted, etc
4. I lay out ALL my supplies and everything I need (including large syringes for measuring, jars, pg/vg, etc) before I touch the bottle of nic!
5. When I'm ready for the nic (again, everything else is laid out and ready) I wear gloves, eye protection, and am PAINFULLY careful about every movement I make with the stuff.
When everything is finished, everything gets rinsed well in warm water
thoroughly in the sink...sealed jars of base, empty nic bottle, everything. Afterwards, If it can go in the dishwasher it goes (prob not a good idea if you have kids around!) in, anything else after rinsing is left to soak in the sink until I wash (immediately after putting everything else away). The work area is thoroughly washed even though I've never spilled a drop.
Them last but not least, I wash my hands WITH gloves on and dry before I remove them.
Everything gets put away, and supplies that were rinsed thoroughly get washed and put away.
After doing that once, I pretty much decided that unless I become DIRT poor all of the sudden, I'm just better off going with 36 mg lol! I would also suggest to anyone THINKING about mixing your own, to at least TRY the process with 36mg first! I did. Bought a 120ml bottle of 36mg nic and a couple of small bottles of pg/vg to see if it was for me before I started investing in mass quantities
Vendors run specials all the time, and it's a great way to dip your toe in the water.