I'll admit I haven't combed through the 67 pages here, but from my moderate skimming I seem to be seeing some confusion here.
Nickel wire changes electrical resistance under temperatures; at a very measurable interval. Your coil calculators will only be telling you how to build based on your RESTING resistance.
As nickel heats up, so does your Ohm reading. This is why everyone who's used Nickel before on anything like a mech or conventional regulators will tell you they hate it, because of its "Awful ramp up time". The DNA40 calculates the resting resistance and presents an algorithm to boost and throttle wattage to maintain your desired temperature. VV devices take amp draw and moderate current pressure in respects to your amps. VW will take amp draw and boost/knock voltage in respects to your resistance. VT devices like the DNA40 will now moderate WATTS and therefor RESISTANCE based on your temperature. The independent variable here has changed; and with it, the name of vaping.
This is the next step.
Keeping your locked variable at watts with conventional regulation tells you how quickly you get to an undisclosed temperature as it plateaus. Because of that, and other circumstances made by juice, airflow, and wicking; You are presented with builds that are either Low ramp up high draw time, or high ramp up low draw time. Abusing these extremes either gives you a dead draw, or a burnt hit.
Temperature regulation will be able to boost or throttle your wattage to get to your temperature as quickly as possible, and moderate it so that it STAYS there. In theory, this can mitigate lost ejuice and wasted battery to virtually perfect efficiency.
If this has been said before, sorry for beating the horse; but if I could inform at least a couple of you fellow vapers, it's all worth the chance.
I really hope that helped clear the air!