I typically never had problems with dry eyes before vaping, but now sometimes I do. I think that staring at ECF contributes just as much as vaping does, if not more, though. I've used eye drops a few times, too. Additionally, I wonder if some of the flavorings contribute, as Atomic Fireball, for example, is very potent and if I don't blow the vapor away from my eyes, it can be a bit irritating.