A good practice is to clean and dry before refilling each time. You'll extend the life of the coils. I don't have the CE5, so I'm not all that sure on how to do it, but I think they have a top coil like my iClear 16's, so I can tell you how I clean those.
Uncrew the clearo from the battery. Remove the drip tip and pour out any remaining liquid. Who knows, maybe you can save some? If you haven't been getting any burnt taste from it, I have poured stuff back into a bottle. Uncrew the base from the plastic tube. Remove and put the silicone cap on top of the inner metal tube somwhere safe, where you won't loose it. If you can replace the coil, you should be able to unscrew that metal tube from the base as well. If you have a type where you can't replace the coil, then just leave it and rinse all the parts in warm water. Dry everything as best you can with a paper towel. Screw the base and the coil back on to your battery. Hold the fire button down two seconds at a time until the coils glow red and are no longer covered in gunk. Place the silicone cap back on top and screw the plastic sleave back on to the base. Pour some liquid in, place the drip tip back, and let it sit for a bit until the wick get resoaked. Vape away.