Is PG safe?

[Jemcases]

I've heard that it could contribute to fatal heart attacks, central nervous system depression, contact dermatitis, liver and heart damage. I hope there is a doctor in the house.

 

[N rustica]

I think it's better than VG, it's been used in medical inhalers since the 1950s. VG doesn't have as long a safety record for being inhaled.

Who keeps spreading this BS about PG? Nobody ever cites a source, they just say "I've heard"

 

[DC2]

I've heard that it could contribute to fatal heart attacks, central nervous system depression, contact dermatitis, liver and heart damage. I hope there is a doctor in the house.

I can't imagine where you heard any of that, but none of it is true.
Not only is PG one of the safest things around, but it very well might be good for you.

 

[Horseman9]

I can't imagine where you heard any of that, but none of it is true.

+ 1 on that. PG is used in many ways in modern life. Including use as an anti-bacterial inhalant, flavor & aroma enhancer. No ill effects have ever been documented, unless you are allergic (and that is a minuscule % of people). Some drying of tissues is about all I'm aware of.

 

[sailorman]

Some say that it causes suicide, psychosis, bedwetting, arthritis, bursitis, bleeding gums, tinnitus, varicose veins, genital warts, toenail fungus, restless leg syndrome and baldness.

Some say wrestlin' is real and the moonshot was fake.

 

[sailorman]

I've heard that it could contribute to fatal heart attacks, central nervous system depression, contact dermatitis, liver and heart damage. I hope there is a doctor in the house.

Hmmm....Does that mean it doesn't contribute to non-fatal heart attacks?

 

[frosting]

I've heard that it could contribute to fatal heart attacks, central nervous system depression, contact dermatitis, liver and heart damage. I hope there is a doctor in the house.

LOL. sorry. that was my initial reaction.

Unless you are allergic to it, I would say it's pretty safe. It's found in food, hair care products, salad dressing, tooth paste, some inhalers, being pumped though hospital ventilation systems and is used on animals to prevent/heal skin ailments.

 

[tj99959]

Just wondering why PG is atomized into the ventilation systems of so many hospitals since it is so bad.

FDA propylene glycol



The federal Food and Drug Administration lists propylene glycol as generally recognized as safe (GRAS) except for use in or on cat food. Because propylene glycol is listed as GRAS, it is subject to many fewer government regulations in general and EPA requirements in particular. The Dow corporation technical data sheet for propylene glycol notes that it is used in the food, cosmetics, pharmaceutical, fragrance, and personal care industries, both as an ingredient and as a low temperature heat transfer agent in the dairy, brewing and ice cream industries, as well as in food storage.


EPA general findings



In general, propylene glycol tested negative in a battery of EPA tests. In a 2006 EPA report titled "Reregistration Eligibility Decision for Propylene Glycol and Dipropylene Glycol," the agency found propylene glycol negative for carcogenicity up to agency testing limit doses. This finding updates the 1991 EPA Integrated Risk Information System (IRIS) carcinogenic assessment for propylene glycol, which at the time had not undergone a human carcinogenic potential evaluation. The 2006 study also found propylene glycol negative for mutagenicity and genotoxic potential.

 

[Jemcases]

Ah yes, ignorance is bliss. So I had to type propylene glycol in my favorite search engine and
I unfortunately do find some very depressing info, although it may just be my e-juice messing with me.

Maybe dow labs has it right:

Propylene glycol (PG or MPG) is a colorless, odorless liquid1 which is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) in 21 CFR § 184.1666, for use as a direct food additive under the conditions prescribed. It is approved by the U.S. FDA for certain indirect food additive uses.2 PG is used in cosmetics and as an excipient (inert solvent or carrier) in pharmaceuticals. PG has a wide range of practical applications such as antifreezes, coolants and aircraft deicing fluids; heat transfer and hydraulic fluids; solvents; food; flavors and fragrances; cosmetics and personal care products; pharmaceuticals; chemical intermediates; plasticizers; and thermoset plastic formulations.3 See Product Uses.
PG is not acutely toxic (single dose, high exposure). It is essentially non-irritating to the skin and mildly irritating to the eyes. Numerous studies support that PG is not a skin sensitizer or a carcinogen.4 See Health Information.
Occupational and consumer exposure is possible because PG is used in a variety of consumer items. See Exposure Potential.
PG is not volatile and is miscible with water. It is not expected to bio-accumulate and it is not acutely toxic to water organisms except at very high concentrations.5 See Environmental Information.
http://www.dow.com/productsafety/finder/prog.htm

 

[frosting]

Ah yes, ignorance is bliss. So I had to type propylene glycol in my favorite search engine and
I unfortunately do find some very depressing info, although it may just be my e-juice messing with me.

Maybe dow labs has it right:

Propylene glycol (PG or MPG) is a colorless, odorless liquid1 which is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) in 21 CFR § 184.1666, for use as a direct food additive under the conditions prescribed. It is approved by the U.S. FDA for certain indirect food additive uses.2 PG is used in cosmetics and as an excipient (inert solvent or carrier) in pharmaceuticals. PG has a wide range of practical applications such as antifreezes, coolants and aircraft deicing fluids; heat transfer and hydraulic fluids; solvents; food; flavors and fragrances; cosmetics and personal care products; pharmaceuticals; chemical intermediates; plasticizers; and thermoset plastic formulations.3 See Product Uses.
PG is not acutely toxic (single dose, high exposure). It is essentially non-irritating to the skin and mildly irritating to the eyes. Numerous studies support that PG is not a skin sensitizer or a carcinogen.4 See Health Information.
Occupational and consumer exposure is possible because PG is used in a variety of consumer items. See Exposure Potential.
PG is not volatile and is miscible with water. It is not expected to bio-accumulate and it is not acutely toxic to water organisms except at very high concentrations.5 See Environmental Information.
Propylene Glycol

Nothing depressing about that. Some of the harsher things listed it is added to in order to make things safer.

 

[cricque]

Nothing is 200% safe, even eating/drinking nothing isn't safe
PG is even a substance in analogs, so you have been smoking it (if you were a former smoker)



And I quote

The acute oral toxicity of propylene glycol is very low, and large quantities are required to cause perceptible health damage in humans; propylene glycol is metabolized in the human body into pyruvic acid (a normal part of the glucose-metabolism process, readily converted to energy), acetic acid (handled by ethanol-metabolism), lactic acid (a normal acid generally abundant during digestion),[11] and propionaldehyde (a highly toxic substance).[12][13][14] Serious toxicity generally occurs only at plasma concentrations over 1 g/L, which requires extremely high intake over a relatively short period of time.[15] It would be nearly impossible to reach toxic levels by consuming foods or supplements, which contain at most 1 g/kg of PG. Cases of propylene glycol poisoning are usually related to either inappropriate intravenous administration or accidental ingestion of large quantities by children.[16] The potential for long-term oral toxicity is also low. In one study, rats were provided with feed containing as much as 5% PG in feed over a period of 104 weeks and they showed no apparent ill effects.[17] Because of its low chronic oral toxicity, propylene glycol was classified by the U. S. Food and Drug Administration as "generally recognized as safe" (GRAS) for use as a direct food additive.

Taken from Propylene glycol - Wikipedia, the free encyclopedia

 

[Benzin]

fatal heart attacks, central nervous system depression, contact dermatitis, liver and heart damage. ???
mhhhh...