I have 2 boxers left...one passed away last week. They don't seem to mind it one way or the other...they give it the same reaction, and that is to leave the room. After they ate a few packs of smokes in their puppy years and getting sick, they want nothing to do with anything cigarette related...and in their minds, vaping is the same as smoking cigarettes. However...they always want to smell the juices before I load them up.