I've used both and would say they are different. First off the 510 connection on the clearo is silver in appearance and gold on the megas. The coil on the clearo is vertical, located near the base of the carto, and has no wicking material inside the coil. The coil on the megas is horizontal, located about half way up the carto, and has added wicking material inside the
coils.
My personal preference is for the single coil clearos because with my daily
eliquid I get better taste and vapor production. However, I prefer the tube from the megas for looks and durability. So I actually remove the clear tube and replace it with a mega tube.