This was on another forum and worked for me - mix vodka and glycerin 50/50 and drip a couple of drops onto the atty - pull on it heavily for a few drags without inhaling - drip a couple more drops and repeat a few times. It seems to clean out the initial primer and get the atty broken in quickly. I spent about 30 hours reading up before deciding which to go with and decided on the 510. I'll probably end up trying a few others - just wish there was a universal charger available. Or maybe I'll find adaptors for other atomizers from 510 at a reasonable price.