I talked a lot about detoxing and what else is in tobacco besides nic in my first post on here.
I also discussed WHY you MAY be feeling increased panic and arousal while detoxing.
I also discussed various solutions like Swedish snus and WTA (whole tobacco alkaloids and how they may help you.
I don't really love repeating myself.
But basically, there are substances in tobacco besides nicotine that are psychoactive, including MAOI-A and MAOI-B. They are powerful anti-anxiety and anti-depressant chemicals, and I talked at length about what they do, about brain homeostasis and withdrawal.
Because you are getting nicotine ONLY by vaping, you will be detoxing off the very things that can make tobacco more relaxing and soothing. There are safer ways to slowly wean yourself off these substances during detox, as even TAR has been shown to have a psychoactive effect in the brain in a NIH study.
Basically, while detoxing, your brain will be "starved" of these other substances. Persons with an underlying susceptibility to anxiety and depression often have a harder time with that, as tobacco may have been "treating" your anxiety via a MAOI process.
As far as detox, physical detox is usually done within 2 weeks. The amount of time it takes your brain to upregulate substances that tobacco was supplying can take anywhere from 1--3 months, depending on your brain, how much you were smoking, and etc. Some folks find it easier to use "detox" aids as I mentioned.
If you want to stay with straight nic, that's fine. I'd expect panic attacks and hype arousal to be worse during that time frame, but it should eventually fall off. Too much nic can certainly exacerbate anxiety, so lowering it is a fine idea, as I also said.
Drink lots of water, lower your nic, and decide if you need more "help" to detox. Sometimes, it can be easier to taper cigarettes slowly over time to reduce the amount of "detox" you have to do all at once. That choice is up to you.
Anna