Only way to know really would be to try it.
I think the closer you get to zero nicotine, the less you notice the effects of nicotine, but that's been my experience.
I went from 18mg to 12 mg about two years ago. Over the last year I've dropped from 12mg to 3mg. I probably could go down to zero nic at this point, but I keep telling myself that I still like a little bit of nic in my vape.
I'm not familiar with the cleito. If it is a sub-tank, your requirements for nicotine would be less than if you were using a normal resistance tank.
Not sure if this was helpful at all.