- Jan 15, 2011
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Great column, thought I'd share.
http://www.wausaudailyherald.com/ar...343/Dan-Newman-column-me-vaping-beats-smoking
http://www.wausaudailyherald.com/ar...343/Dan-Newman-column-me-vaping-beats-smoking
--The idea that nicotine is a poison
--The idea that nicotine is "the most addictive substance known to man"
The first argument is a red herring, and the second simply isn't even close to being true.
And those arguments are going to come back to bite us some day.
One of the primary principles of toxicology is that the dose makes the poison.I'm a newbie to vaping, so please don't climb all over me. Two questions ... How is nicotine being a poison a red herring, and, how is nicotine being the most addictive substance known to man not even close to being true? As far as I know, nicotine, in high dosages, IS a poison, and it IS one of the most addictive substances known to man, if not THE most addictive. That's what makes it so hard to quit ... the strength of the addiction. Is there something I'm not seeing?
Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties. However, after coadministration with an MAOI, such as those found in tobacco, nicotine produces significant behavioral sensitization, a measure of addiction potential.
Tobacco smoke contains the monoamine oxidase inhibitors harman, norharman, anabasine, anatabine, and nornicotine. These compounds significantly decrease MAO activity in smokers. MAO enzymes break down monoaminergic neurotransmitters such as dopamine, norepinephrine, and serotonin. It is thought that the powerful interaction between the MAOI's and the nicotine is responsible for most of the addictive properties of tobacco smoking.
Those opposed to e-cigarettes are famous for lying and over exaggerating.I'm a newbie to vaping, so please don't climb all over me. Two questions ... How is nicotine being a poison a red herring, and, how is nicotine being the most addictive substance known to man not even close to being true? As far as I know, nicotine, in high dosages, IS a poison, and it IS one of the most addictive substances known to man, if not THE most addictive. That's what makes it so hard to quit ... the strength of the addiction. Is there something I'm not seeing?
Can you provide me with links which support your statements?
I just want the information so I can make my own informed decisions, I'm not trying to call you out on your opinions.