PG vs VG

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Krazirob

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there have actually been more rumors and drama started around PG than VG....i would like to see some of this research or articles about studies on ecigs using PG only........but besides the point i wouldn't go with a certain ratio based on your concerns of what you are inhaling and how healthy or unhealthy it can be........best cigarettes any day....

and the flavor is the flavor and it separate from the VG and PG. I've gotten the same flavor off PG based as VG based.....adjusting power can bring a flavor in or out depending on wick.....

just my 2 cents though
 

Krazirob

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I never go below 80/20, all the studies done on ecigs are done with PG not VG, we really have no idea what inhaling VG will do.

Vegetable Glycerin studies


Glycerol is one of the most benign organic liquids known to man. It is hype-allergenic, non-carcinigeic, non teratogenic and non-mutagenic. It is metabolized quite easily by a process called beta-oxidation. This process results in the production of CO2 and H2O and is a quite normal, common, and natural catabolic process.

The following is a few excerpts from a study called SIDS initial assessment profile of Glycerol Citation

Glycerol is of low toxicity when injested, inhaled, or in contact with skin
The NOACE for local irritant effects to the upper respiratory tract is 165 mg/m3
Glycerol is of a low order of acute oral and dermal toxicity with LD50 values in excess of 4000 mg/kw bw.
Glycerol has low potential to irritate the skin and the eye
Glycerol is not a skin sensitiser
Glycerol does not induce gene mutations in bacterial strains, chromosomal effects in mammalian cells or primary dna damage in vitro
Overall, glycerol is not considered to possess genotoxic potential
No effects on fertility and reproductive performance were observed
No further work is indicated by this study, because of the low hazard potential of this substance.




FROM ANOTHER STUDY regarding PG

Studies have been done in hospital wards using PG in an air-sterilization application. In these
studies, humans were exposed to saturated and super saturated atmospheres for prolonged
periods without adverse effects.12 In 1971, the uptake of PG mist by humans was studied using
a 10% solution in labeled deionized water which was nebulized into a mist tent. Less then 5%
of the mist entered the body, and of this 5%, 90% lodged in the nasopharynx and rapidly disappeared
into the stomach. Very little PG was found in the lungs. 12
Robertson and coworkers (1947) exposed monkeys and rats to atmospheres saturated with PG
vapor and found no adverse effects in animals after periods of 12 to 18 months.30 Rats exposed
to a 90-day inhalation study using PG aerosol at concentrations up to 2,200 mg/m3 (160, 1000
and 2200 mg/m3), for 6 hours/day, 5 days/week did not demonstrate systemic toxicity. However,
it was reported that there was a significant increase in the number of goblet cells (a type of
secretory cell found in the top layer of the intestinal and respiratory tract that secretes mucus)
and/or an increase in the mucin content of the existing goblet cells in the nasal passages of rats
exposed to the high and medium doses. In addition, the PG concentration in this study caused
nasal hemorrhage and ocular discharge in a high proportion of animals, all of these reversible
effects are considered to be the result of dehydration of the nares and eyes.23 The dehydration
would be expected with PG, as it is a hydroscopic material and can cause irritation simply by
removing excess water from the eyes and nasal passages.
Minute changes in cilia cell structures were observed after rabbits had been exposed to 10%
PG for 20 minutes by inhalation. It was reported that the goblet cells were discharging mucous
or were completely exhausted.


 
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vjc0628

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really depends n a lot of thing's

including the vendor
there are a lot of very flavorful 100% vg ie boba's bounty, velvet cloud vapor does a few
the best ratio on copper crack House blend is 40/60

there are also a lot of 80/20 mix that are lacking in flav and vice versa

I find many times if I'm going for a sharper flav I go heavier PG
If I'm going for creamier I go more VG

A lot depends on your equipment as well

I'm sure there are a lot of other factors as well
 

BardicDruid

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Vegetable Glycerin studies


Glycerol is one of the most benign organic liquids known to man. It is hype-allergenic, non-carcinigeic, non teratogenic and non-mutagenic. It is metabolized quite easily by a process called beta-oxidation. This process results in the production of CO2 and H2O and is a quite normal, common, and natural catabolic process.

The following is a few excerpts from a study called SIDS initial assessment profile of Glycerol Citation

Glycerol is of low toxicity when injested, inhaled, or in contact with skin
The NOACE for local irritant effects to the upper respiratory tract is 165 mg/m3
Glycerol is of a low order of acute oral and dermal toxicity with LD50 values in excess of 4000 mg/kw bw.
Glycerol has low potential to irritate the skin and the eye
Glycerol is not a skin sensitiser
Glycerol does not induce gene mutations in bacterial strains, chromosomal effects in mammalian cells or primary dna damage in vitro
Overall, glycerol is not considered to possess genotoxic potential
No effects on fertility and reproductive performance were observed
No further work is indicated by this study, because of the low hazard potential of this substance.




FROM ANOTHER STUDY regarding PG

Studies have been done in hospital wards using PG in an air-sterilization application. In these
studies, humans were exposed to saturated and super saturated atmospheres for prolonged
periods without adverse effects.12 In 1971, the uptake of PG mist by humans was studied using
a 10% solution in labeled deionized water which was nebulized into a mist tent. Less then 5%
of the mist entered the body, and of this 5%, 90% lodged in the nasopharynx and rapidly disappeared
into the stomach. Very little PG was found in the lungs. 12
Robertson and coworkers (1947) exposed monkeys and rats to atmospheres saturated with PG
vapor and found no adverse effects in animals after periods of 12 to 18 months.30 Rats exposed
to a 90-day inhalation study using PG aerosol at concentrations up to 2,200 mg/m3 (160, 1000
and 2200 mg/m3), for 6 hours/day, 5 days/week did not demonstrate systemic toxicity. However,
it was reported that there was a significant increase in the number of goblet cells (a type of
secretory cell found in the top layer of the intestinal and respiratory tract that secretes mucus)
and/or an increase in the mucin content of the existing goblet cells in the nasal passages of rats
exposed to the high and medium doses. In addition, the PG concentration in this study caused
nasal hemorrhage and ocular discharge in a high proportion of animals, all of these reversible
effects are considered to be the result of dehydration of the nares and eyes.23 The dehydration
would be expected with PG, as it is a hydroscopic material and can cause irritation simply by
removing excess water from the eyes and nasal passages.
Minute changes in cilia cell structures were observed after rabbits had been exposed to 10%
PG for 20 minutes by inhalation. It was reported that the goblet cells were discharging mucous
or were completely exhausted.


You missed one thing, VG is oil based, PG isn't, and if you read the studies on ecigs, they clearly state whats in the liquid and VG has never been there.
 

Slots

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PG is a germicide.
It's been used in the ventilation systems of hospitals, office buildings, nursing homes, etc. to combat airborne infection since the late 50s to prevent the spread of germs.
Is the basic ingredients in Sno-Cone, as it makes the flavoring "stick" to the ice.
Used in asthma inhalers, aerosol air fresheners, babyfood, pills, all kinds of food in the grocery store, in cosmetics like lipstick etc etc
PG, which has already been mentioned is antimicrobial, is for the most part the primary ingredient in our e-juice.
And either it, VG, or a combination are used in fog machines, in dance halls, and at concerts.
It's currently the base chemical used for a new breathing treatment being studied to combat rejection in lung transplant patients.
Long live our e-cigs ..... Haven't had a cold, etc since I started vaping.
 
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ShariR

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There are posts on ECF from people who have a sensitivity to either pg or vg. I have read that pg carries the flavor better than vg. When using all vg the amount of flavor supposedly needs to be increased. I do not know which is better or which is right. If you do searches on these topics you will find plenty to read and can make your own decision.

I also have read that the studies on ecigs have been with pg based liquids. I have not read these studies so can not comment. The Health forum has a lot of material that you can read about these topics.
 

Fulgurant

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I made a great discovery today while dripping and yes I like vapor and usually get 65/35 or 50/50 but I had the opportunity to drip a 50/50 vs an 80/20 and the taste difference was astonishing! Also I had just as much vapor production with dripping the 80/20- is this true only for dripping?what ratios do u use?

For what it's worth, I too was surprised when I compared the vapor production between juices at 80/20 PG/VG and juices at max VG%. There was a difference to be sure, but it wasn't as marked a difference as I expected given all of the talk about VG's vapor production. The differences between mixes that are somewhere in the middle of the scale will be much less noticeable.

By the same token, the difference in flavor seems similarly subtle, but that comparison is subject to a wide range of variation based on the particular flavors present in a given juice. Some juices seem extremely flavorful at max VG; others seem muted.

When given the choice (and absent any other info), I generally default to 80/20 for juices that I have yet to try, because that's as close to a presumed industry standard as I can get, and therefore I must presume that the 80/20 ratio will convey the flavor profile most faithfully representative of the mixer's intention. But once I've established that I like a flavor, I tend to order 70/30 or 65/35. The vapor produced by those ratios is ever so slightly smoother, and the juice tends to darken/thicken (carmelize) in my tanks slower than it does at 80/20.

As always, mileage will vary. I'd caution against taking anything you read as gospel on this subject though. No one can tell you exactly what you'll perceive/prefer. Experimentation is the only way to know.
 

Krazirob

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You missed one thing, VG is oil based, PG isn't, and if you read the studies on ecigs, they clearly state whats in the liquid and VG has never been there.

true but thats besides the point.......they have done studies on the two ingredients separately......whether it was in regards to ecigs doesn't matter....what matters is they have done research on PG and VG inhalation on the body.......nothing wrong with these two ingredients...
 

Chas_L

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You missed one thing, VG is oil based, PG isn't, and if you read the studies on ecigs, they clearly state whats in the liquid and VG has never been there.

There are numerious threads here on ECF by those who vape only VG be it with Nic, without Nic flavored or unflavored.

Most if not all Official Studies are very suspect at best. I for one prefer to read post of those with real world experience and from what I have read more have negative reactions to PG than to VG.
 
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firephly

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I've decided I think I really prefer a high VG or 100% VG over PG. PG makes a scratchy dry feeling in my mouth and throat especially now that the weather has turned dryer and the air is dry already, and I think that the VG actually gives a better flavor (contrary to what I always hear).
I like the smooth velvety mouth feel of the VG and the thick luscious vapor.
 
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