Excellent answer, and true. Nicotine is a vasoconstrictor, and the tiny veins that service skin can't receive enough blood to nourish it. As my dermatologist told me on my last visit, "Your skin is shot."
Note that this repetitious, daily vasoconstriction will also cause long-term damage to eyes, ears, organs and sexual function. It's all part of the price nic addicts will pay -- some day. And e-smoking doesn't avoid those problems if nicotine continues to be inhaled. Add hardening of the arteries to your list, as well, along with cholesterol imbalances.