I read the above about wicking, smaller means better.
At first 500 shorted and burnt through too easy for me. 400 lasted. I got better at wrapping (I guess) and shorting wasn't as much of an issue. I'm using up my 500 and one of my tend to be thick liquids is having wicking problems.
I pulled out the screw and the liquid travels through the tube fine but it won't come through to the outside.
So far that's the only liquid with that problem, although it is my most used liquid.
I haven't really noticed much of a difference in wicking (until the one that seems clogged).
I suggest you buy a couple precut packs of 400 and 500 to see what you like before jumping into buying a sheet.