Locating nicotine receptors
Cosgrove and colleagues scanned the brains of 52 men and 58 women, about half of whom were smokers. The researchers examined nicotine receptors in the brain by using a radioactive marker that binds specifically to an important group of receptors that are primarily responsible for the body's physical dependence on nicotine, Cosgrove said.
Smokers in the study had abstained from smoking for a week so that their nicotine receptors would be free to bind to the marker used for imaging.
The researchers found that male smokers had about 16 percent more nicotine receptors in an area of their brain known as the striatum, 17 percent more in the cerebellum, and 13 to 17 percent more in the cortical region, or outside layer, of the brain compared with male nonsmokers. Female smokers, on the other hand, had similar numbers of nicotine receptors in these brain regions.
Why are female brains different?
Dr. Len Horovitz, a pulmonary specialist at Lenox Hill Hospital in N.Y., agreed more attention should be paid to non-nicotine related smoking therapies.
"You can replace all the nicotine you want, and people might still want to smoke," Horovitz said. For instance, smoking is a big stress reliever for some people. Even the act of deep breathing is a part of the habit, and breathing exercises may help smokers because they mimic puffing a cigarette, Horovitz said.
Read more: Why women find it harder to quit smoking | Fox News
One question we failed to ask in our CASAA survey of e-cigarette users was gender. Any guesses whether there are more male than female users or vice versa?

I got my step sister and her friend interested and they both ordered pink eGo type PVs.

