I've mainly used kanthal, but have also used nichrome, and didn't really notice a difference in flavor. Recently I noticed I was getting a pretty big difference in flavor with 2 similar drippers with about the same build, but one was kanthal and the other nichrome. I rebuilt the dripper that had nichrome with kanthal and the taste was back to normal.
The difference was pretty substantial for the juice I was testing, an extracted tobacco. The tobacco notes were muted quite a bit with the nichrome and the cherry flavor added had a different taste. I don't think all juices are effected as much or I probably would have noticed the difference earlier, but trying some more juices I know well on a nichrome build convinced me to stick with kanthal.
One person I know who vapes similar juices also said he doesn't like what nichrome does to flavor, but other than that I haven't seen a similar complaint from others.
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