Your post made me curious, so I put a 28g twisted coil in my SS serpent this morning. I have a few of these Wotofo "comp wire" tubes in 28g twisted, tiger, quad twisted, so I figured it'd be a good time to put them to use.My twisted build works great too. I've tried claptons, fused claptons, SS316 and 304 in TC mode, and twisted kanthal is the best build for me. In this tank twisted coil gives you the best flavour, no matter 2 wires or 3 wires, 26 or 28g. Twisted builds in serpent are just splendid!
I definitely like it better than the MKWS Clapton wire build it replaced, but I really think I don't care for that wire.