Yes, if it worked on the smokalien, it should work on the Istick. Make sure both the tank's pin and the mod's 510 connection are clean and free of eliquid. If pushing down the tank doesn't work, I might consider getting a heat sink to put between the mod and the tank. If your tank's pin is merely too short for your mod, then you can use a heat sink to make a better connection, potentially.
Are you vaping in wattage mode? Is the coil correctly seated? Are the 0-rings all where they need to be? Just some general other things to consider especially if it's a new coil. If you are inadvertently using temperature control with a kanthal coil, that may be your issue.
I think it's probably the connection too, just trying to cover all bases.
Best of luck and welcome to ECF.
Anna