This is a personal preference choice in my opinion.
Pg (propylene glycol) is allegedly a better
flavor carrier than Vg (vegetable glycerin). Vg is a much better
vapor producer.
Most e-liquids will have some ratio mix of both Pg and Vg to have both nice flavor and vapor production. Some people are sensitive or even allergic to Pg; these folks will need to use a 100% Vg liquid. Most of the
e-liquid vendors that do custom mixing offer the option of the Pg/Vg ratio you prefer.
I once ordered my favorite flavor in both a 50/50 Pg/Vg ratio and also in a 100% Vg just to see which one I preferred for future reference. In all honesty, I couldn't tell a difference in flavor between the two, with the 100% Vg
juice having more vapor production. Juices with a larger ratio of Vg may require some steep time for the flavoring agents to acheive their full saturation of the
juice, as Vg is not as good of a flavor carrier as Pg.
If given a choice in Pg/Vg ratio, I tend to keep it simple and order a 50/50 ratio, or going with more Vg depending upon the flavor or how much more vapor I want based on previous experience with that flavor. Sometimes more Pg can add some harshness, sometimes more Vg can cause wicking issues because of it's thicker viscosity. Vg can be thinned down with some distilled water.