I think a lot of folks get hooked on 50/50 because that's the default mix in the samples that FSUSA ships in every order, so many of us are impressed with it and stick with it. I usually go with 60/40 myself, I've played with the mixes a bit and that seems to be the best for me, personally- because I like a little bit extra throat hit. Of course, I've also noticed that this is highly dependent on the flavor- some flavors have a ton of throat hit regardless, some don't have much at all.