Do you mean a flavor difference in the wicking material? Like silica vs. cotton? If so, I have heard there is a flavor difference, but I've only ever used the cotton provided with my subtank mini so far. As far as vapor, I don't think the wicking material would cause much of a difference as long as it's staying wet.
I beg to differ on the wicking material doesn't matter as long as its wet
Silica - is OK, comes with a lot of stock clearos and protank coils. You can dryburn it to clean but hassle to work with. Good to have 1mm onhand for solving protank gurgling and flooding issues by replacing the flavor wicks.
Ekowool - better than silica, cleaner tasting. Easier to work with since its hollow in the middle you can slide a pin through to make wrapping a coil easier. Can dryburn to clean and lasts quite a while or until you burn the coil.
Cotton - Simple to use, easy to find, wicks good but can't dryburn and lucky to get 3 days before having to rewick. Burns easily in the coil
Hemp fiber - Wicks and holds juice better than cotton, lasts longer on the coil(up to a week and more) before rewicking. Bit of hassle since you should pick out the off colored shards or you have a woodzy breakin taste. Can't dryburn. I used hemp fiber for well over a year in my PT builds and still using it.
Cellucotton(Rayon) - Great wicking in RBA, kayfuns and the sort. Lasts until the coil is cocooned with burnt juice and still looks clean in the middle. Easy to work with and very inexpensive(15 bucks for 500'). You have to overstuff the coil and trim the bulk off the tails since cellucotton contracts when juiced unlike cotton/hemp that expand when juiced or you will be prone to dryhits from lack of coil contact of the wicking thus burning the material.
My only con with cellucotton was that it doesn't work well in protank builds as well as like kayfuns. I would enjoy my vape for the first tank then I would have to pull like crazy to get a decent vape so I stopped using it in my PT builds but have has nothing short of success with using cellucotton in any other atty especially my kayfuns
This is my opinion of the 5 wicking materials that I have used over the last 2 years I have been rebuilding and just to add I get my wire from Temco.