MAOIs and stress
A few further thoughts on MAOIs and smoking/vaping :
There is a group of people for whom nicotine alone is mostly effective but not always - and the not always is times of stress (a typical post : No matter how much I vape, I still want to smoke analogs (and i still do smoke) Havent quit yet, who's in this category?). "So I really stopped. Until I got stressed. I vaped the hell out of my PV and wasn't finding it taking off the edge of the stress. I was getting my fix for sure, but found it wasn't the nicotine that was causing my craving. So now I smoke occasionally as a stress manager. I vape for nicotine."
Hence the need for MAOIs is probably related to stress / anxiety and can be thought of as 'everyday (modern life) stress' as much as a type of 'clinical depression'; some people are more anxiety-prone (not necessarily a 'bad thing'), more perfectionist, 'worriers' one might say ('less careless' to put it positively).
[ The following article mentions that MAOIs have had sucess in smoking cessation, though no sources are stated : MAOI - What is it? - Description, MAOI Side Effects, Usage, Warnings and More ]
I see this post as a start at defining what the MAOI need is and which people most need it.
This has all been rather taken as given, but making a stab at explicitly stating the notion might lead to further insights and hone the idea.
Further, I might blunderingly suggest that as anxiety-proneness is a 1-D scale, about 1/3 will have no particular interest in the MAOI aspect of 'smoking', 1/3 will need it sometimes and 1/3 will feel it is 'something mssing' from nic-only vaping. This latter 1/3 would be many of the people who don't 'take to' vaping - a sizable percentage; perhaps as much as half for those who at least continue some level of tobacco use (behavioural factors for non-transferance aside; I would guestimate succesful transference at about 30-40%).
Hence WTA (Whole Tobacco Alkaloids, not just nicotine but the MAOIs as well), or nicotine plus MAOI, e-liquids (an optional choice like PG or VG) could significantly increase the sucessful switch to vaping as a far safer alternative to smoking.
The simple-minded equating of smoking with nicotine intake has been a major 'oversight' in the health promotion by smoking reduction/cessation field; given that this insight is not particularly new (there are patents on MAOIs for NRT use dating back as least as far as 2002 plus research articles dating much further back), one could reasonably call it something of a disaster.
There is a group of people for whom nicotine alone is mostly effective but not always - and the not always is times of stress (a typical post : No matter how much I vape, I still want to smoke analogs (and i still do smoke) Havent quit yet, who's in this category?). "So I really stopped. Until I got stressed. I vaped the hell out of my PV and wasn't finding it taking off the edge of the stress. I was getting my fix for sure, but found it wasn't the nicotine that was causing my craving. So now I smoke occasionally as a stress manager. I vape for nicotine."
Hence the need for MAOIs is probably related to stress / anxiety and can be thought of as 'everyday (modern life) stress' as much as a type of 'clinical depression'; some people are more anxiety-prone (not necessarily a 'bad thing'), more perfectionist, 'worriers' one might say ('less careless' to put it positively).
[ The following article mentions that MAOIs have had sucess in smoking cessation, though no sources are stated : MAOI - What is it? - Description, MAOI Side Effects, Usage, Warnings and More ]
I see this post as a start at defining what the MAOI need is and which people most need it.
This has all been rather taken as given, but making a stab at explicitly stating the notion might lead to further insights and hone the idea.
Further, I might blunderingly suggest that as anxiety-proneness is a 1-D scale, about 1/3 will have no particular interest in the MAOI aspect of 'smoking', 1/3 will need it sometimes and 1/3 will feel it is 'something mssing' from nic-only vaping. This latter 1/3 would be many of the people who don't 'take to' vaping - a sizable percentage; perhaps as much as half for those who at least continue some level of tobacco use (behavioural factors for non-transferance aside; I would guestimate succesful transference at about 30-40%).
Hence WTA (Whole Tobacco Alkaloids, not just nicotine but the MAOIs as well), or nicotine plus MAOI, e-liquids (an optional choice like PG or VG) could significantly increase the sucessful switch to vaping as a far safer alternative to smoking.
The simple-minded equating of smoking with nicotine intake has been a major 'oversight' in the health promotion by smoking reduction/cessation field; given that this insight is not particularly new (there are patents on MAOIs for NRT use dating back as least as far as 2002 plus research articles dating much further back), one could reasonably call it something of a disaster.
Last edited:
