I have oral lichen planus which I thought was from vaping. well apparently over use of ibuprofin also causes this. I was taking at least 2 to 6 ibuprofin pills everyday for the last 15 years for my back. within a month of not taking it anymore the oral issues have almost completely cleared up. it was so bad I could literally feel my gums throbbing. I am so happy it is better because it is precurser of oral cancer and DANG did that biopsy hurt like a mother!!!