Gallup Poll finds 48% of former smokers in US reported quitting “cold turkey”, 5% with skin patch, 3% with e-cigarettes, 2% with prescription drug

Vocalek;10309757 said:
How many times do I have to tell you? The Polosa studies were NOT smoking cessation studies.

Smoking cessation studies recruit people who want to quit smoking. In Polosa's studies, anyone who said s/he was interested in quitting was excluded from the study. The purpose of the studies were to determine whether e-cigarettes could help those who don't want to (or can't) quit to at least reduce the number of cigarettes per day they smoke, thereby exposing them to fewer toxins and carcinogens. There was a pilot study that used 40 subjects, and it was the 24-month follow-up that Siegel was writing about. The full study recruited 300 people who did not want to quit, and divided them into three groups, testing three different dosages of nicotine.

Those studies would more properly be categorized as smoking reduction studies.

And what, pray tell, would be the adequate control group for such a study? One-third of the people in the full study were getting cartridges with zero nicotine. An "inactive" treatment is what usually serves as a control group in smoking cessation studies. For example, in studies of the patch, the active group got nicotine in their patches and the control group got patches with no drug.


Me? You've never told me anything, ever.


But, from the Reuters article:

1. It did not, however, compare the devices to traditional nicotine replacement therapies, such as gum or patches.

The full range of nicotine-replacement therapies (NRT's) have to be compared against each other. The Polosa study did not do that.

2. Since there was no control group of smokers who got no e-cigarettes at all, it's hard to know how many would have quit smoking on their own by the end of a year, experts noted.

..or would have reduced smoking on their own without inducement, I might add.

A control group is essential to making the case for a bulletproof study. Polosa did not have a control. But it is a beginning, and that's good.


You're an advocate, you have a particular position and thereby a particular axe to grind.

And that's also, in this case, good, because I am a vaper - just not a blind one.


I am a scientist professionally. I often encounter the null hypothesis. I respect it. YMMV.

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